Trial reportPloS one2017
Intermittent hypoxic training improves anaerobic performance in competitive swimmers when implemented into a direct competition mesocycle.
Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The Effects of Intermittent Hypoxic Training Strategies on Maximal Oxygen Uptake in Healthy Humans: A Meta-analysis with Meta-regression.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- The effect of hypoxic interventions on swimming performance in competitive athletes: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Aerobic Intermittent Hypoxic Training Is Not Beneficial for Maximal Oxygen Uptake and Performance: A Systematic Review and Meta-Analysis.Scandinavian journal of medicine & science in sports · 2025Pooled it
- Effects of Passive or Active Recovery Regimes Applied During Long-Term Interval Training on Physical Fitness in Healthy Trained and Untrained Individuals: A Systematic Review.Sports medicine - open · 2024Pooled it
- Hepcidin response to three consecutive days of endurance training in hypoxia.European journal of applied physiology · 2021Trial
- Hypoxia and exercise interactions on skeletal muscle insulin sensitivity in obese subjects with metabolic syndrome: results of a randomized controlled trial.International journal of obesity (2005) · 2020Trial
- Impact of the administration type for normobaric hypoxia on the maximal aerobic capacity: A systematic review and meta-analysis.Sports medicine and health science · 2026Review
- Moderate Normobaric Hypoxia Does Not Exacerbate Left Ventricular Dysfunction After Exhaustive Exercise in Athletes and Untrained Individuals.Journal of clinical medicine · 2025Article
- Comparative effectiveness of physical training modalities on swimming performance: a two-tier network meta-analysis.Frontiers in physiology · 2025Review
- Effects of concurrent heat and hypoxic training on cycling anaerobic capacity in men.Scientific reports · 2024Article
- Recommendations for Women in Mountain Sports and Hypoxia Training/Conditioning.Sports medicine (Auckland, N.Z.) · 2024Review
- Article
- Hypoxia inducible factor-1α related mechanism and TCM intervention in process of early fracture healing.Chinese herbal medicines · 2024Review
- Intermittent Hypoxia Conditioning: A Potential Multi-Organ Protective Therapeutic Strategy.International journal of medical sciences · 2023Review
- Review
- Article
- Chronic Exposure to Normobaric Hypoxia Increases Testosterone Levels and Testosterone/Cortisol Ratio in Cyclists.International journal of environmental research and public health · 2022Article
- Acute Physiological Response to Different Sprint Training Protocols in Normobaric Hypoxia.International journal of environmental research and public health · 2022Article
- Article
- Effects of Interval Training Under Hypoxia on Hematological Parameters, Hemodynamic Function, and Endurance Exercise Performance in Amateur Female Runners in Korea.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on anaerobic and aerobic capacity and swimming performance in well-trained swimmers. Sixteen male swimmers were randomly divided into a hypoxia (H) group (n = 8), which trained in a normobaric hypoxia environment, and a control (C) group (n = 8), which exercised under normoxic conditions. However, one participant left the study without explanation. During the experiment group H trained on land twice per week in simulated hypoxia (FiO2 = 15.5%, corresponding to 2,500 m a.s.l); however, they conducted swim training in normoxic conditions. Group C performed the same training program under normoxic conditions. The training program included four weekly microcyles, followed by three days of recovery. During practice sessions on land, the swimmers performed 30 second sprints on an arm-ergometer, alternating with two minute high intensity intervals on a lower limb cycle ergometer. The results showed that the training on land caused a significant (p<0.05) increase in absolute maximal workload (WRmax) by 7.4% in group H and by 3.2% in group C and relative values of VO2max by 6.9% in group H and 3.7% in group C. However, absolute values of VO2max were not significantly changed. Additionally, a significant (p<0.05) increase in mean power (Pmean) during the first (11.7%) and second (11.9%) Wingate tests was only observed in group H. The delta values of lactate concentration (ΔLA) after both Wingate tests were significantly (p<0.05) higher in comparison to baseline levels by 28.8% in group H. Opposite changes were observed in delta values of blood pH (ΔpH) after both Wingate tests in group H, with a significant decrease in values of ΔpH by 33.3%. The IHT caused a significant (p<0.05) improvement in 100m and 200m swimming performance, by 2.1% and 1.8%, respectively in group H. Training in normoxia (group C), resulted in a significant (p<0.05) improvement of swimming performance at 100m and 200m, by 1.1% and 0.8%, respectively. In conclusion, the most important finding of this study includes a significant improvement in anaerobic capacity and swimming performance after high-intensity IHT. However, this training protocol had no effect on absolute values of VO2max and hematological variables.
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Registered trials
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