Evidence map›Paper›PMID 28763325›Full record

ArticleAmerican journal of physical medicine & rehabilitation2018

Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis?

Augustine C Lee, Rina M Bloch, William F Harvey, Jeffrey B Driban, Lori Lyn Price, Xingyi Han, Chenchen Wang

Abstract read
In one paragraph

Article in American journal of physical medicine & rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Augustine C LeeFrom the Center for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, Massachusetts (ACL, WFH, JBD, XH, CW); Department of Physical Medicine and Rehabilitation, Tufts Medical Center, Boston, Massachusetts (RMB); Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts (LLP); and Tufts Clinical and Translational Science Institute, Tufts University, Boston, Massachusetts (LLP).
Rina M Bloch
William F Harvey
Jeffrey B Driban
Lori Lyn Price
Xingyi Han
Chenchen Wang
Tufts Medical Center · US

Funding

Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
Tai Chi for Knee OsteoarthritisR01AT005521 · NCCIH · TUFTS MEDICAL CENTER · PI WANG, CHENCHEN · 2010 to 2013
$2.4M
Mentoring and Research in Patient-Oriented Integrative MedicineK24AT007323 · NCCIH · TUFTS MEDICAL CENTER · PI WANG, CHENCHEN · 2014 to 2023
$1.8M
NCATS NIH HHS UL1 TR001064NCCIH NIH HHS K24 AT007323NCCIH NIH HHS R01 AT005521
6 · The paper itself

Abstract

objectivesMobility activity modifications indicate early functional losses that act as precursors to future declines among community-dwelling older adults. However, there is scarce evidence on whether activity modifications indicate poorer physical health among adults with symptomatic osteoarthritis, a major cause of disability. Our purpose was to investigate whether patient-reported mobility activity modifications indicated poorer physical health among adults with symptomatic knee osteoarthritis.

designSecondary cross-sectional analysis of randomized trial data was performed. Preclinical Disability Questionnaire was used to group participants into the following three categories: difficulty, modified, and no difficulty walking/stair climbing. Kruskal Wallis and χ tests were used to compare clinical factors across groups.

resultsAmong 121 participants (median age = 60 yrs; 73% female; 60% white), less than 10% had modified walking/stair climbing. Compared with those with no walking difficulty, participants with modified walking had significantly less balance (P = 0.01) and global health (P = 0.01) as well as greater knee pain (P = 0.05) and physical disability (P = 0.04). Those with modified stair climbing had significantly smaller walking distances (P = 0.03) compared with those with no difficulty stair climbing.

conclusionsActivity modifications may signal early impairments in physical health among people with symptomatic knee osteoarthritis. If confirmed, patient-reported activity modifications may enhance symptom evaluation in osteoarthritis and enable a better understanding of the disablement process.

Indexed as

Mobility LimitationAdultChi-Square DistributionCross-Sectional StudiesDisability EvaluationExerciseFemaleHumansKnee JointMaleMiddle AgedOsteoarthritis, KneePhysical Therapy ModalitiesPostural BalanceRandomized Controlled Trials as TopicRange of Motion, Articular

Identifiers

PMID28763325
PMCPMC5771810
OpenAlexW2741153999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.