ArticleTranslational psychiatry2017
Genome-wide association analysis identifies common variants influencing infant brain volumes.
Article in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders.Biological psychiatry · 2023Pooled it
- TwinEQTL: ultrafast and powerful association analysis for eQTL and GWAS in twin studies.Genetics · 2022Pooled it
- The Impact of OXTR, COMT, and GRIN2B Polymorphisms on Brain Development in Preterm Infants.Journal of clinical medicine · 2025Article
- Rare Copy Number Variants Reveal Critical Cell Types and Periods of Brain Development in Neurodevelopmental Disorders.Biological psychiatry global open science · 2025Article
- Common genetic variation associated with adult subcortical brain volume is also associated with subcortical brain volume at birth.Frontiers in neuroscience · 2025Article
- Effect of schizophrenia common variants on infant brain volumes: cross-sectional study in 207 term neonates in developing Human Connectome Project.Translational psychiatry · 2023Article
- Structural neuroimaging phenotypes and associated molecular and genomic underpinnings in autism: a review.Frontiers in neuroscience · 2023Review
- Emerging concepts involving inhibitory and activating RNA functionalization towards the understanding of microcephaly phenotypes and brain diseases in humans.Frontiers in cell and developmental biology · 2023Review
- Influence of gonadal steroids on cortical surface area in infancy.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes.Neurobiology of aging · 2022Article
- Review
- SNORD116 and growth hormone therapy impact IGFBP7 in Prader-Willi syndrome.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Neurological Disorders Associated with WWOX Germline Mutations-A Comprehensive Overview.Cells · 2021Review
- Placental genomic risk scores and early neurodevelopmental outcomes.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Genome-Wide Association Analysis of Neonatal White Matter Microstructure.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- WWOX Loss of Function in Neurodevelopmental and Neurodegenerative Disorders.International journal of molecular sciences · 2020Review
- DRD2 methylation and regional grey matter volumes in young adult offspring from families at ultra-high risk for alcohol dependence.Psychiatry research. Neuroimaging · 2019Article
- Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development.Scientific reports · 2019Article
- A review on neuroimaging studies of genetic and environmental influences on early brain development.NeuroImage · 2019Review
- Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus.Neurobiology of disease · 2019Article
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
Abstract
Genome-wide association studies (GWAS) of adolescents and adults are transforming our understanding of how genetic variants impact brain structure and psychiatric risk, but cannot address the reality that psychiatric disorders are unfolding developmental processes with origins in fetal life. To investigate how genetic variation impacts prenatal brain development, we conducted a GWAS of global brain tissue volumes in 561 infants. An intronic single-nucleotide polymorphism (SNP) in IGFBP7 (rs114518130) achieved genome-wide significance for gray matter volume (P=4.15 × 10
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.