Evidence map›Paper›PMID 28763012›Full record

ArticleCancers2017

Performance of a RT-PCR Assay in Comparison to FISH and Immunohistochemistry for the Detection of ALK in Non-Small Cell Lung Cancer.

David R Hout, Brock L Schweitzer, Kasey Lawrence, Stephan W Morris, Tracy Tucker, Rosetta Mazzola, Rachel Skelton, Frank McMahon, John Handshoe, Mary Lesperance and 2 more

Abstract read
In one paragraph

Article in Cancers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David R HoutInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. dhout@insightgenetics.com.
Brock L SchweitzerInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. bschweitzer@insightgenetics.com.
Kasey LawrenceInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. klawrence@insightgenetics.com.
Stephan W MorrisInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. smorris@insightgenetics.com.
Tracy TuckerDepartment of Pathology and Laboratory Medicine, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada. ttucker2@bccancer.bc.ca.
Rosetta MazzolaDepartment of Medical Oncology, British Columbia Cancer Agency, VIC 2410 Lee Avenue, Victoria, BC V8R 6V5, Canada. rosetta.mazzola@alumni.ubc.ca.
Rachel SkeltonInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. rachelleahskelton@gmail.com.
Frank McMahonInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. fmcmahon@insightgenetics.com.
John HandshoeInsight Genetics, Inc., Suite 510, 2 International Plaza, Nashville, TN 37217, USA. jhandshoe@insightgenetics.com.
Mary LesperanceDepartment of Mathematics and Statistics, University of Victoria, Box 1700, STN CSC, Victoria, BC V8W 2Y2, Canada. mlespera@uvic.ca.
Aly KarsanDepartment of Pathology and Laboratory Medicine, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada. akarsan@bccancer.bc.ca.
David L SaltmanDepartment of Medical Oncology, British Columbia Cancer Agency, VIC 2410 Lee Avenue, Victoria, BC V8R 6V5, Canada. david.saltman@bccancer.bc.ca.

Funding

NCI NIH HHS HHSN261201200047C
6 · The paper itself

Abstract

Patients with lung cancers harboring an activating anaplastic lymphoma kinase (

Indexed as

anaplastic lymphoma kinasefluorescence in situ hybridizationimmunohistochemistrynon-small cell lung cancerreverse transcriptase-polymerase chain reaction

Identifiers

PMID28763012
PMCPMC5575602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.