Evidence map›Paper›PMID 28762866›Full record

ArticleTissue engineering. Part A2018

In Vitro Bioactivity of One- and Two-Dimensional Nanoparticle-Incorporated Bone Tissue Engineering Scaffolds.

Jason T Rashkow, Gaurav Lalwani, Balaji Sitharaman

Abstract read
In one paragraph

Article in Tissue engineering. Part A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Nano-bio interactions of 2D molybdenum disulfide.Advanced drug delivery reviews · 2022
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason T RashkowDepartment of Biomedical Engineering, Stony Brook University , Stony Brook, New York.
Gaurav LalwaniDepartment of Biomedical Engineering, Stony Brook University , Stony Brook, New York.
Balaji SitharamanDepartment of Biomedical Engineering, Stony Brook University , Stony Brook, New York.

Funding

Nanotechnology-based Theranostic Technology for Bone Tissue EngineeringDP2OD007394 · OD · STATE UNIVERSITY NEW YORK STONY BROOK · PI SITHARAMAN, BALAJI · 2010 to 2010
$2.4M
NIH HHS DP2 OD007394
6 · The paper itself

Abstract

This study investigates the effect of incorporation of one- or two-dimensional nanoparticles with distinct composition and morphology on the bioactivity of biodegradable, biocompatible polymer matrices. 0.2 wt% multiwalled carbon nanotubes, multiwalled graphene nanoribbons, graphene oxide nanoplatelets (GONPs), molybdenum disulfide nanoplatelets (MSNPs), or tungsten disulfide nanotubes (WSNTs) were uniformly dispersed in poly(lactic-co-glycolic acid) (PLGA) polymer. PLGA or nanoparticle-incorporated PLGA were then incubated with simulated body fluid (SBF) under physiological conditions for 1, 3, 7, or 14 days. Apatite collection on control and incorporated scaffolds was assessed. All groups showed apatite precipitate on the surface after 1 day of SBF incubation. After 14 days of SBF incubation, scaffolds incorporated with GONPs, MSNPs, or WSNTs showed significantly higher phosphate accumulation compared to PLGA scaffolds. Scaffolds incorporated with GONPs, MSNPs, or WSNTs should be studied in vivo to further investigate potential bioactivity, leading to enhanced integration and tissue repair at the bone-implant interface.

Indexed as

Bone and BonesNanoparticlesNanotubes, CarbonTissue EngineeringTissue ScaffoldsTungstenNanotubes, CarbonTungstenbioactivitybiocompatiblenanoparticlepolymerscaffold

Identifiers

PMID28762866
PMCPMC5905874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.