Evidence map›Paper›PMID 28762170›Full record

ArticleWorld journal of surgery2017

Pheochromocytoma with Synchronous Ipsilateral Adrenal Cortical Adenoma.

M Earth Hasassri, T K Pandian, Aleh A Bobr, Irina Bancos, William F Young, Melanie L Richards, David R Farley, Geoffrey B Thompson, Travis J McKenzie

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Article in World journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M Earth HasassriMayo Medical School, Rochester, MN, USA.
T K PandianDivision of Subspecialty General Surgery, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN, 55901, USA.
Aleh A BobrDepartment of Laboratory Medicine and Pathology, Minneapolis, MN, USA.
Irina BancosDivision of Endocrinology and Metabolism, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
William F YoungDivision of Endocrinology and Metabolism, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Melanie L RichardsDivision of Subspecialty General Surgery, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN, 55901, USA.
David R FarleyDivision of Subspecialty General Surgery, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN, 55901, USA.
Geoffrey B ThompsonDivision of Subspecialty General Surgery, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN, 55901, USA.
Travis J McKenzieDivision of Subspecialty General Surgery, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN, 55901, USA. McKenzie.Travis@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPheochromocytoma with synchronous ipsilateral adrenal cortical adenoma (PSCA) may present with mixed clinical, biochemical, and radiological features characteristic to each neoplasm subtype.

methodsAll patients with a pathological diagnosis of pheochromocytoma were evaluated for an ipsilateral cortical adenoma from 1994 through 2015. Retrospectively extracted data included indications for adrenalectomy, diagnostic workup (biochemical and radiographic), operative characteristics, pathological findings, and postoperative complications.

resultsSixteen of 413 patients (4%) undergoing adrenalectomy for pheochromocytoma had a PSCA. Median patient age was 57.7 years (IQR 50.1, 63.1); 50% were male. On imaging, 75% of the adrenal neoplasms were found incidentally and only 50% were reported to have a synchronous ipsilateral neoplasm based on imaging findings. Clinically important cortical hormone secretion was diagnosed in 38% of these patients; 25% had glucocorticoid secretory autonomy; and 13% had primary aldosteronism.

conclusionPhysicians should be aware that adrenal neoplasms with mixed diagnostic findings may represent PSCA. Evaluation should be performed on this co-occurrence to prevent perioperative complications from resection of an unexpected secretory cortical neoplasm.

Indexed as

Adrenal Cortex HormonesAdrenal Cortex NeoplasmsAdrenalectomyAdrenal Gland NeoplasmsAdrenocortical AdenomaAdultAgedFemaleGlucocorticoidsHumansHyperaldosteronismMaleMiddle AgedNeoplasms, Multiple PrimaryPheochromocytomaPostoperative ComplicationsAdrenal Cortex HormonesGlucocorticoids

Identifiers

PMID28762170

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.