SynthesisWiener klinische Wochenschrift2017
Moderate alcohol consumption and atherosclerosis : Meta-analysis of effects on lipids and inflammation.
Synthesis in Wiener klinische Wochenschrift, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Moderate alcohol consumption and lipoprotein subfractions: a systematic review of intervention and observational studies.Nutrition reviews · 2022Pooled it
- Trial
- The Role of Obesity in the Association Between Alcohol Consumption and HDL-c Levels: Baependi Heart Study.Lipids · 2026Article
- [Smoking and nicotine use, heated tobacco products, psychological and socioeconomic aspects of dependence, alcohol, infections, vaccination and diabetes mellitus (Update 2026)].Wiener klinische Wochenschrift · 2026Review
- Interaction Between Composite Dietary Antioxidant Index and Alcohol Consumption on Cardiovascular Diseases: NHANES 2005-2018.Clinical cardiology · 2026Article
- Association of the apolipoproteins with retinal arteriosclerosis in a health examination population.Frontiers in cardiovascular medicine · 2026Article
- Association between alcohol consumption and carotid atherosclerosis in Russia.Scientific reports · 2025Article
- Modifiable and Non-Modifiable Risk Factors and Vascular Damage Progression in Type 2 Diabetes: A Primary Care Analysis.Journal of clinical medicine · 2025Article
- Associations between clinical AUDIT-C screens and HDL cholesterol are observed across primary care patient subgroups.Alcohol, clinical & experimental research · 2025Article
- Endothelial Homeostasis Under the Influence of Alcohol-Relevance to Atherosclerotic Cardiovascular Disease.Nutrients · 2025Review
- The prevalence and determinants of alcohol use in the adult population of Tehran: insights from the Tehran Cohort Study (TeCS).Clinical and experimental medicine · 2025Article
- Up-to-date advance in the relationship between obstructive sleep apnea and heart failure: a narrative review.Sleep & breathing = Schlaf & Atmung · 2024Review
- Dyslipidemias: Prevalence and Associated Factors among Lactating Women in a Lower- and Middle-Income Country, Ghana.Journal of lipids · 2023Article
- [Smoking, heated tobacco products, alcohol and diabetes mellitus (update 2023)].Wiener klinische Wochenschrift · 2023Article
- Associations between Alcohol Consumption and HDL Subspecies Defined by ApoC3, ApoE and ApoJ: the Cardiovascular Health Study.Current problems in cardiology · 2023Review
- Acute and chronic blood serum proteome changes in patients with methanol poisoning.Scientific reports · 2022Article
- Alcohol, Drinking Pattern, and Chronic Disease.Nutrients · 2022Review
- Alcohol Consumption and Cardiovascular Disease Risk: Placing New Data in Context.Current atherosclerosis reports · 2022Review
- Alcohol, cardiovascular disease and industry funding: A co-authorship network analysis of systematic reviews.Social science & medicine (1982) · 2021Article
- Moderate dose alcohol protects against serum amyloid protein A1-induced endothelial dysfunction via both notch-dependent and notch-independent pathways.Alcoholism, clinical and experimental research · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlcohol consumption plays an important role in the risk of major cardiovascular diseases. We conducted a meta-analysis to summarize the association between moderate alcohol consumption and atherosclerosis.
designIn this study four databases and reference lists of retrieved articles were searched to identify eligible studies. A meta-analysis was carried out of all interventional studies that assessed the effects of moderate alcohol consumption on concentrations of low density lipoprotein cholesterol, high density lipoprotein cholesterol, triglycerides, apolipoprotein A I, interleukin 6, plasminogen activator inhibitor 1, fibrinogen, and other biomarkers previously found to be associated with risk of atherosclerosis.
resultsA total of 31 studies met the eligibility criteria. In response to moderate alcohol consumption, low density lipoprotein cholesterol decreased by 0.08 mmol/l (P = 0.05), and high density lipoprotein cholesterol increased by 0.08 mmol/l (P < 0.00001), whereas total cholesterol and triglyceride remained the same. Moreover, interleukin 6 decreased by 0.43 pg/ml (P = 0.03), whereas C‑reactive protein and tumor necrosis factor a remained the same. Several hemostatic factors and adiponectin were modestly affected by alcohol consumption.
conclusionModerate alcohol consumption is causally related to lower risk of atherosclerosis through changes in lipid profiles and inflammation.
Indexed as
Identifiers
28762059What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.