Evidence map›Paper›PMID 28762049›Full record

ArticleEnvironmental science and pollution research international2018

Biogenic synthesis of gold nanoparticles from Terminalia arjuna bark extract: assessment of safety aspects and neuroprotective potential via antioxidant, anticholinesterase, and antiamyloidogenic effects.

Natarajan Suganthy, Vijayan Sri Ramkumar, Arivalagan Pugazhendhi, Giovanni Benelli, Govindaraju Archunan

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Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Review
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  5. Green-mediated gold nanoparticles fromBiotechnology notes (Amsterdam, Netherlands) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
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  15. Frontiers in chemistry · 2025
    Article
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  18. Article
  19. RSC advances · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natarajan SuganthyDepartment of Nanoscience and Technology, Alagappa University, Karaikudi, Tamil Nadu, India. suganthy.n@gmail.com.
Vijayan Sri RamkumarDepartment of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Arivalagan PugazhendhiGreen Processing, Bioremediation and Alternative Energies Research Group, Faculty of Environment and Labour Safety, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Giovanni BenelliDepartment of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124, Pisa, Italy.
Govindaraju ArchunanCentre for Pheromone Technology, Department of Animal Science, Bharadhidasan University, Tiruchirappalli, Tamil Nadu, India. garchu56@yahoo.co.in.

Funding

UGC DR.S.Kothari Post doctoral fellowship F.4-2/2006(BSR)/BL/13-14/0312UGC kothari post doctoral fellow F.4-2/2006(BSR)/BL/13-14/0345
6 · The paper itself

Abstract

The development of neuroprotective drugs through eco-friendly production routes is a major challenge for current pharmacology. The present study was carried out to synthesize gold nanoparticles (AuNPs) through biogenic route using ethanolic bark extract of Terminalia arjuna, a plant of high interest in Asian traditional medicine, and to evaluate its neuroprotective effects. The synthesized AuNPs were characterized by UV-Vis spectroscopy, FTIR spectroscopy, XRD, FESEM, EDX, HRTEM, DLS, and zeta potential analyses. UV-Vis spectroscopy showed a characteristics SPR absorption band at 536 nm specific for AuNPs. XRD, TEM, and FESEM analyses revealed the formation of face-centered cubic crystalline, spherical and triangular shaped AuNPs, with size ranging between 20 and 50 nm. DLS and ZP analysis illustrated that the average size of AuNPs was 30 nm, which was found to be stable at 45 mv. The neuroprotective potential of AuNPs was evaluated by assessing its antioxidant, cholinesterase inhibitory, and antiamyloidogenic activities. AuNPs showed dose-dependant inhibition of acetylcholinesterase and butyrylcholinesterase with IC

Indexed as

AntioxidantsCholinesterase InhibitorsCholinesterasesGoldLeukocytes, MononuclearMetal NanoparticlesPlant ExtractsSpectroscopy, Fourier Transform InfraredSpectrum AnalysisTerminaliaAntioxidantsCholinesterase InhibitorsCholinesterasesGoldPlant ExtractsAlzheimer’s diseaseCholinesteraseDanio rerioGold nanocrystalsβ-Amyloid peptide

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.