Evidence map›Paper›PMID 28761977›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Calcineurin inhibitors regulate fibroblast growth factor 23 (FGF23) synthesis.

Ludmilla Bär, Claudia Großmann, Michael Gekle, Michael Föller

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Investigation of Copy Number Variations (CNVs) of the GoatAnimals : an open access journal from MDPI · 2022
    Article
  7. Article
  8. Osteocytic FGF23 and Its Kidney Function.Frontiers in endocrinology · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ludmilla BärInstitute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, 06120, Halle (Saale), Germany.
Claudia GroßmannInstitute of Physiology, Martin Luther University Halle-Wittenberg, 06120, Halle (Saale), Germany.
Michael GekleInstitute of Physiology, Martin Luther University Halle-Wittenberg, 06120, Halle (Saale), Germany.
Michael FöllerInstitute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, 06120, Halle (Saale), Germany. michael.foeller@landw.uni-halle.de.ORCID http://orcid.org/0000-0002-8678-7785
Martin Luther University Halle-Wittenberg · DE

Funding

Deutsche Forschungsgemeinschaft Fo 695/2-1
6 · The paper itself

Abstract

Fibroblast growth factor 23 (FGF23) inhibits renal phosphate reabsorption and calcitriol formation, effects depending on Klotho as a co-receptor for FGF23. In addition, FGF23/Klotho strongly influences aging and the onset of age-associated diseases. The synthesis of FGF23 by bone cells is induced by store-operated Ca

Indexed as

AnimalsCalcineurinCalcineurin InhibitorsCell LineCyclosporineFibroblast Growth Factor-23Fibroblast Growth FactorsGene Expression RegulationNFATC Transcription FactorsRatsRNA, MessengerTacrolimusTranscription Factor RelACalcineurinCalcineurin InhibitorsCyclosporineFibroblast Growth Factor-23Fibroblast Growth FactorsNFATC Transcription FactorsRNA, MessengerTacrolimusTranscription Factor RelACalciumCiclosporinKlothoPhosphatasePhosphateTacrolimus

Identifiers

PMID28761977
OpenAlexW2741385165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.