Evidence map›Paper›PMID 28761676›Full record

ArticleOpen heart

Characterisation of clot microstructure properties in stable coronary artery disease.

Ahmed Sabra, Matthew James Lawrence, Robert Aubrey, Daniel Obaid, Alexander Chase, Dave Smith, Phillip Thomas, Sharon Storton, Gareth R Davies, Karl Hawkins and 3 more

Abstract read
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The Impact of Patient Characteristics and Antiplatelet Regimes on Clot Microstructure in Patients Treated for ST Elevation Myocardial Infarction: Clot Microstructure can Evaluate Therapeutic Efficacy.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ahmed SabraNISCHR Haemostasis Biomedical Research Unit, Morriston Hospital, ABMU Health Board, Swansea, UK.
Matthew James LawrenceNISCHR Haemostasis Biomedical Research Unit, Morriston Hospital, ABMU Health Board, Swansea, UK.
Robert AubreyNISCHR Haemostasis Biomedical Research Unit, Morriston Hospital, ABMU Health Board, Swansea, UK.
Daniel ObaidCardiac Centre, Morriston Hospital, ABMU Health Board, Swansea, UK.
Alexander ChaseCardiac Centre, Morriston Hospital, ABMU Health Board, Swansea, UK.
Dave SmithCardiac Centre, Morriston Hospital, ABMU Health Board, Swansea, UK.
Phillip ThomasCardiac Centre, Morriston Hospital, ABMU Health Board, Swansea, UK.
Sharon StortonNISCHR Haemostasis Biomedical Research Unit, Morriston Hospital, ABMU Health Board, Swansea, UK.
Gareth R DaviesNISCHR Haemostasis Biomedical Research Unit, Morriston Hospital, ABMU Health Board, Swansea, UK.
Karl HawkinsNISCHR Haemostasis Biomedical Research Unit, College of Medicine, Swansea University, Swansea, UK.
Phylip Rhodri WilliamsCollege of Engineering, Swansea University, Swansea, UK.
Keith MorrisSchool of Applied Science, Cardiff Metropolitan University, Cardiff, UK.
Phillip Adrian EvansNISCHR Haemostasis Biomedical Research Unit, Morriston Hospital, ABMU Health Board, Swansea, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery disease (CAD) is associated with an increased prothrombotic tendency and is also linked to unfavourably altered clot microstructure. We have previously described a biomarker of clot microstructure (d

methodsA blood sample prior to angiography was obtained from 251 consecutive patients undergoing diagnostic coronary angiography. Patients were categorised based on angiographic findings as presence or absence of obstructive CAD (stenosis ≥50%). The blood sample was assessed using the d

resultsA significant difference (p=0.028) in d

conclusionsFor the first time, we characterise clot microstructure, as measured by d

Indexed as

atherosclerosisclot microstructurecoagulationcoronary angiographycoronary artery disease

Identifiers

PMID28761676
PMCPMC5515126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.