Evidence map›Paper›PMID 28761652›Full record

ArticleBMJ open diabetes research & care2017

Incidence of severe hypoglycemia in children with type 1 diabetes in the Nordic countries in the period 2008-2012: association with hemoglobin A

N H Birkebaek, A K Drivvoll, K Aakeson, R Bjarnason, A Johansen, U Samuelsson, T Skrivarhaug, A V Thorsson, J Svensson

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  16. The Evolution of Hemoglobin ADiabetes care · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 6 countries.

N H BirkebaekDepartment of Pediatrics, Aarhus University Hospital, Aarhus, Denmark.
A K DrivvollNorwegian Childhood Diabetes Registry, Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
K AakesonDepartment of Pediatrics, County Hospital Ryhov, Jönköping, Sweden.
R BjarnasonMedical Center, Landspitali University Hospital, Reykjavik, Iceland.
A JohansenDepartment of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
U SamuelssonDepartment of Pediatrics, Linköping University Hospital, Linköping, Sweden.
T SkrivarhaugNorwegian Childhood Diabetes Registry, Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
A V ThorssonMedical Center, Landspitali University Hospital, Reykjavik, Iceland.
J SvenssonCopenhagen Diabetes Research Center (CPH-DIRECT), Department of Children and Adolescents, Copenhagen University Hospital, Herlev, Denmark.
National University Hospital of Iceland · ISAarhus University Hospital · DKDiabetes Australia · AUDiabetes Research CenterLinköping University Hospital · SEOslo University Hospital · NORigshospitalet · DKRyhov Hospital Jönköping · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTreatment of type 1 diabetes has been intensified aiming at normalizing blood glucose, which may increase the risk of severe hypoglycemia (SH). We aimed to compare the incidence of SH events in the four Nordic countries Denmark, Iceland, Norway and Sweden, and to assess the influence of hemoglobin A1c (HbA RESEARCH DESIGN AND

methodsData on children below 15 years with a diabetes duration more than 1 year, registered in the national childhood diabetes databases in the four Nordic countries from 2008 to 2012, were compiled. Data completeness was more than 95%.

resultsTotally 8806 (48% females) patients with 29 715 person years were included, mean age and diabetes duration were 11 years and 5.1 years, respectively. The overall rate of SH was 6.0 per 100 patient-years, and did not change during the study period. The Swedish population constantly had the lowest SH incidence while it decreased significantly in the Danish population. HbA

conclusionsRisk of SH differs between the Nordic countries with the lowest risk in Sweden. Pump therapy was associated with decreased risk of SH. The low HbA

Indexed as

HbA1cinsulin pumpNordic countriesSevere hypoglycemiatarget HbA1c.

Identifiers

PMID28761652
PMCPMC5530237
OpenAlexW2617402021

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.