Evidence map›Paper›PMID 28761624›Full record

ArticleOxidative medicine and cellular longevity2017

Pitaya Extracts Induce Growth Inhibition and Proapoptotic Effects on Human Cell Lines of Breast Cancer via Downregulation of Estrogen Receptor Gene Expression.

Deborah de Almeida Bauer Guimarães, Danielle Dos Santos Bonfim De Castro, Felipe Leite de Oliveira, Eduardo Matos Nogueira, Marco Antônio Mota da Silva, Anderson Junger Teodoro

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Unveiling multifaceted effects ofFood chemistry: X · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Potential Apoptotic Activities ofPlants (Basel, Switzerland) · 2022
    Article
  9. The complete plastomes of red fleshed pitaya (Physiology and molecular biology of plants : an international journal of functional plant biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deborah de Almeida Bauer GuimarãesNutritional Biochemistry Core, Food and Nutrition Program, UNIRIO, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-9714-9674
Danielle Dos Santos Bonfim De CastroNutritional Biochemistry Core, Food and Nutrition Program, UNIRIO, Rio de Janeiro, RJ, Brazil.
Felipe Leite de OliveiraLaboratory of Proliferation and Cell Differentiation, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Eduardo Matos NogueiraLaboratory of Genomics, Molecular and Cellular Biology Program, UNIRIO, Rio de Janeiro, RJ, Brazil.
Marco Antônio Mota da SilvaLaboratory of Technology Natural Products, UEZO, Rio de Janeiro, RJ, Brazil.
Anderson Junger TeodoroNutritional Biochemistry Core, Food and Nutrition Program, UNIRIO, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-0949-9528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is one of the most prevalent cancers in the world and is also the leading cause of cancer death in women. The use of bioactive compounds of functional foods contributes to reduce the risk of chronic diseases, such as cancer and vascular disorders. In this study, we evaluated the antioxidant potential and the influence of pitaya extract (PE) on cell viability, colony formation, cell cycle, apoptosis, and expression of BRCA

Indexed as

Breast NeoplasmsCactaceaeCell DivisionFemaleG2 PhaseGene Expression Regulation, NeoplasticHumansMCF-7 CellsNeoplasm ProteinsPlant ExtractsReceptors, EstrogenNeoplasm ProteinsPlant ExtractsReceptors, Estrogen

Identifiers

PMID28761624
PMCPMC5518493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.