Evidence map›Paper›PMID 28761616›Full record

ArticleThe Pan African medical journal2017

Cardiometabolic risk among HIV-POSITIVE Ugandan adults: prevalence, predictors and effect of long-term antiretroviral therapy.

Patrick Kazooba, Ivan Kasamba, Billy Nsubuga Mayanja, Joseph Lutaakome, Ivan Namakoola, Tino Salome, Pontiano Kaleebu, Paula Munderi

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Physical activity and hypertension amongst HIV-positive and HIV-negative populations in rural South Africa.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Observational
  7. Article
  8. Cardiometabolic health in people with HIV: expert consensus review.The Journal of antimicrobial chemotherapy · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Cardiovascular disease risk in women living with HIV.Current opinion in HIV and AIDS · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Patrick KazoobaMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Ivan KasambaMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Billy Nsubuga MayanjaMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Joseph LutaakomeMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Ivan NamakoolaMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Tino SalomeMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Pontiano KaleebuMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Paula MunderiMRC/UVRI Uganda Research Unit on AIDS, P.O. Box 49, Entebbe, Uganda.
Uganda Virus Research Institute · UGLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MC_U950080928
6 · The paper itself

Abstract

introductionWe investigated the prevalence, predictors of and effect of Antiretroviral Therapy (ART) regimen on cardiometabolic risk among HIV-positive Ugandan adults at enrolment into a prospective cohort to study the Complications of Long-Term ART (CoLTART).

methodsWe collected data on cardiometabolic risk factors including dyslipidemia, hypertension, hyperglycemia, obesity and calculated the mean atherogenic index for Plasma (AIP) and 10 year Framingham risk score (FHS). Exposures were: ART regimen, duration on ART, demographic, socio-economic, behavioral, and life-style factors including smoking, physical activity and diet (including fruit and vegetables consumption).

resultsWe enrolled 1024 participants, 65% female, mean age was 44.8 years (SD 8.0) and median duration on ART was 9.4 years (IQR 6.1-9.8). The prevalence of abdominal obesity was 52.6%, BMI≥25 kg/m

conclusionART increases cardiometabolic risk. Integration of routine assessment for cardiometabolic risk factors and preventive interventions into HIV care programs in resource-limited settings is recommended.

Indexed as

AdolescentAdultAge FactorsAnti-HIV AgentsCardiovascular DiseasesCohort StudiesFemaleHIV InfectionsHumansLinear ModelsLipidsMaleMetabolic DiseasesMiddle AgedMultivariate AnalysisPrevalenceAnti-HIV AgentsLipidscardiometabolicdyslipidemiaHIVhypertensionlong-term ARTobesity

Identifiers

PMID28761616
PMCPMC5516660
OpenAlexW2616027219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.