Evidence map›Paper›PMID 28761427›Full record

ArticleNeural regeneration research2017

High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges.

Zhi-Wei Ren, Yong-Jie Li, Tao Yu, Duan-Yu Ni, Guo-Jun Zhang, Wei Du, Yuan-Yuan Piao, Xiao-Xia Zhou

Abstract read
In one paragraph

Article in Neural regeneration research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhi-Wei RenBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.
Yong-Jie LiBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.ORCID 0000-0001-8889-3568
Tao YuBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.
Duan-Yu NiBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.
Guo-Jun ZhangBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.
Wei DuBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.
Yuan-Yuan PiaoBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.
Xiao-Xia ZhouBeijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical electrical stimulation-induced afterdischarges remain unclear. In the present study, we examined the effects of different brief-pulse stimulation frequencies (5, 50 and 100 Hz) on cortical electrical stimulation-induced afterdischarges in 10 patients with refractory epilepsy. Results demonstrated that brief-pulse stimulation could terminate cortical electrical stimulation-induced afterdischarges in refractory epilepsy patients. In conclusion, (1) a brief-pulse stimulation was more effective when the afterdischarge did not extend to the surrounding brain area. (2) A higher brief-pulse stimulation frequency (especially 100 Hz) was more likely to terminate an afterdischarge. (3) A low current intensity of brief-pulse stimulation was more likely to terminate an afterdischarge.

Indexed as

afterdischargescortical electrical stimulationfunctional brain mappinghigh frequency stimulationintractable epilepsylow frequency stimulationnerve regenerationneural regenerationneuromodulation

Identifiers

PMID28761427
PMCPMC5514869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.