ReviewTexas Heart Institute journal2017
Potential Role of Patent Foramen Ovale in Exacerbating Hypoxemia in Chronic Pulmonary Disease.
Review in Texas Heart Institute journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Linking patent foramen ovale with atrial cardiomyopathy: a narrative review of clinical signals, electrophysiology, and translational opportunities.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Review
- Platypnea-Orthodeoxia Syndrome Revealing an Undiagnosed Patent Foramen Ovale: A Case Report.Cureus · 2025Article
- Patent foramen ovale as a rare cause of sudden refractory hypoxemia: a case report.Frontiers in cardiovascular medicine · 2025Article
- Exercise-induced Right-to-left Shunt in a Patient with Combined Pulmonary Fibrosis and Emphysema.Internal medicine (Tokyo, Japan) · 2025Article
- Paradoxical Hypoxemia Following Positive Pressure Ventilation: Exploring the Pathophysiology.European journal of case reports in internal medicine · 2024Article
- Patent Foramen Ovale-Induced Platypnea-Orthodeoxia Syndrome: A Case Report and Literature Review.Cureus · 2022Article
- Multi-modal and multi-postural assessment of platypnea-orthodeoxia syndrome triggered by stroke: A case report.Journal of cardiology cases · 2022Article
- Unexplained hypoxemia in COPD with cardiac shunt.Respiratory medicine case reports · 2022Article
- An unusual case of orthodeoxia.Journal of cardiology cases · 2021Article
- Catheter-directed therapies for pulmonary embolism: considerations for patients with patent foramen ovale.Journal of thrombosis and thrombolysis · 2021Review
- Association Between Arterial Oxygen Saturation and Lung Ultrasound B-Lines After Competitive Deep Breath-Hold Diving.Frontiers in physiology · 2021Article
- Obstructing Chiari Network Facilitating Blood Flow Across a Patent Foramen Ovale Causing Hypoxia.JACC. Case reports · 2020Article
- Pulmonary arterial hypertension populations of special interest: portopulmonary hypertension and pulmonary arterial hypertension associated with congenital heart disease.European heart journal supplements : journal of the European Society of Cardiology · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patent foramen ovale has been associated with multiple pulmonary diseases, such as pulmonary hypertension, platypnea-orthodeoxia syndrome, and chronic obstructive pulmonary disease. A connection between patent foramen ovale and chronic pulmonary disease was first described more than 2 decades ago in case reports associating patent foramen ovale with more severe hypoxemia than that expected based on the severity of the primary pulmonary disease. It has been suggested that patients with both chronic pulmonary disease and patent foramen ovale are subject to severe hypoxemia because of the right-to-left shunt. Furthermore, investigators have reported improved systemic oxygenation after patent foramen ovale closure in some patients with chronic pulmonary disease. This review focuses on the association between chronic pulmonary disease and patent foramen ovale and on the dynamics of a right-to-left shunt, and it considers the potential benefit of patent foramen ovale closure in patients who have hypoxemia that is excessive in relation to the degree of their pulmonary disease.
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