ArticleCancer management and research2017
The impact of examined lymph node count on survival in squamous cell carcinoma and adenocarcinoma of the uterine cervix.
Article in Cancer management and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Examined lymph node counts affected the staging and survival in cervical cancer: a retrospective study using the SEER and Chinese cohort.Annals of medicine · 2025Article
- Investigating the prognostic significance of examined lymph node count in elderly women with cervical carcinoma: a SEER population-based study.Frontiers in medicine · 2025Article
- Association between examined lymph node count and survival in resectable cervical cancer: a retrospective analysis using SEER data.Frontiers in oncology · 2025Article
- Article
- Prognostic analysis of stage IIIC1p cervical cancer patients.Frontiers in oncology · 2024Article
- Prognostic analysis of patients with stage IIIC1p cervical cancer treated by surgery.World journal of surgical oncology · 2023Article
- Development and validation of the novel subclassification of pN3 for patients with esophageal cancer.Frontiers in oncology · 2023Article
- Metastatic lymph nodes and prognosis assessed by the number of retrieved lymph nodes in gastric cancer.World journal of gastrointestinal surgery · 2022Article
- Impact of examined lymph node number on lymph node status and prognosis in FIGO stage IB-IIA cervical squamous cell carcinoma: A population-based study.Frontiers in oncology · 2022Article
- Prognostic value of the number of the metastatic lymph nodes in locally early-stage cervical cancer: squamous cell carcinoma versus non-squamous cell carcinoma.Archives of gynecology and obstetrics · 2021Article
- Prognostic Nomogram for Overall Survival of Patients Aged 50 Years or Older with Cervical Cancer.International journal of general medicine · 2021Article
- Impact of examined lymph node count on staging and long-term survival of patients with node-negative stage III gastric cancer: a retrospective study using a Chinese multi-institutional registry with Surveillance, Epidemiology, and End Results (SEER) data validation.Annals of translational medicine · 2020Article
- Risk Stratification Based on Metastatic Pelvic Lymph Node Status in Stage IIIC1p Cervical Cancer.Cancer management and research · 2020Article
- The prognostic value of lymph node ratio in stage IIIC cervical cancer patients triaged to primary treatment by radical hysterectomy with systematic pelvic and para-aortic lymphadenectomy.Journal of gynecologic oncology · 2020Article
- Number of retrieved lymph nodes is an independent prognostic factor after total gastrectomy for patients with stage III gastric cancer: propensity score matching analysis of a multi-institution dataset.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019Article
- Identification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets.Cancer management and research · 2018Article
- Number of Examined Lymph Nodes as a Risk Factor for Recurrence in pT1N+ or pT2-3N0 Gastric Cancer.Cancer diagnosis & prognosisArticle
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe prognostic impact of the number of examined lymph nodes (ELNs) in different histological subtypes of cervical cancer remains unclear. We aimed to assess the impact of the number of ELNs in stage IA2-IIA cervical cancer with different histological subtypes.
methodsData of patients with stage IA2-IIA squamous cell carcinoma (SCC) and adenocarcinoma (AC) of the uterine cervix between 1988 and 2013 were retrieved from the Surveillance, Epidemiology, and End Results program. Univariate and multivariate Cox regression analyses were performed to analyze the effect of number of ELNs on cause-specific survival (CSS) and overall survival (OS).
resultsThe final data set identified 11,830 patients including 7,920 (66.9%) women with SCC and 3,910 (33.1%) with AC. The median number of ELNs was 19. The multivariate analysis indicated that the number of ELNs was an independent prognostic factor influencing CSS and OS, both as a continuous or a categorical variable. Patients with a higher number of ELNs had better survival outcomes. In SCC subtype, the number of ELNs was also the independent prognostic factor of CSS and OS in node-positive patients, but not in patients with node-negative disease. In AC patients, ELN count was not an independent predictor of CSS and OS regardless of lymph node status.
conclusionThe number of ELNs is an independent prognostic factor in patients with stage IA2-IIB cervical cancer. A higher number of ELNs is associated with better survival outcomes, especially in the node-positive SCC subtype.
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