ArticleScientific reports2017
Towards Picogram Detection of Superparamagnetic Iron-Oxide Particles Using a Gradiometric Receive Coil.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- High-Sensitivity Magnetic Particle Spectroscopy Platform for Precise, Specific, and Rapid Detection of Infectious Disease and Cancer-Related Biomarkers.ACS measurement science au · 2026Article
- Multiscale frequency attention transformer for resolution enhancement in magnetic particle imaging.Medical physics · 2026Article
- Magnetic Particle Imaging for Pulmonary Applications: Technological Advances, Biological Insights, and Clinical Translation.Bioengineering (Basel, Switzerland) · 2026Review
- Multi-contrast magnetic particle imaging for tomographic pH monitoring using stimuli-responsive hydrogels.Communications engineering · 2026Article
- Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model.Communications engineering · 2025Article
- Cardiovascular Imaging Applications, Implementations, and Challenges Using Novel Magnetic Particle Imaging.Bioengineering (Basel, Switzerland) · 2025Review
- On the effect of reference and sample volume on magnetic particle imaging quantification.Journal of magnetism and magnetic materials · 2025Article
- Exploring the diagnostic potential: magnetic particle imaging for brain diseases.Military Medical Research · 2025Review
- Advances in engineering nanoparticles for magnetic particle imaging (MPI).Science advances · 2025Review
- Design, construction and validation of a magnetic particle imaging (MPI) system for human brain imaging.Physics in medicine and biology · 2025Article
- Roadmap on magnetic nanoparticles in nanomedicine.Nanotechnology · 2024Review
- Open-source device for high sensitivity magnetic particle spectroscopy, relaxometry, and hysteresis loop tracing.The Review of scientific instruments · 2024Article
- Integrable Magnetic Fluid Hyperthermia Systems for 3D Magnetic Particle Imaging.Nanotheranostics · 2024Article
- Inter-user Comparison for Quantification of Superparamagnetic Iron Oxides with Magnetic Particle Imaging Across Two Institutions Highlights a Need for Standardized Approaches.Molecular imaging and biology · 2023Article
- In vivo tracking of adenoviral-transduced iron oxide-labeled bone marrow-derived dendritic cells using magnetic particle imaging.European radiology experimental · 2023Article
- iMPI: portable human-sized magnetic particle imaging scanner for real-time endovascular interventions.Scientific reports · 2023Article
- Inter-user comparison for quantification of superparamagnetic iron oxides with magnetic particle imaging across two institutions highlights a need for standardized approaches.bioRxiv : the preprint server for biology · 2023Article
- Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions.Biosensors · 2022Review
- [Magnetic particle imaging : From research to the prospect of clinical use].Radiologie (Heidelberg, Germany) · 2022Review
- Adaptive Model for Magnetic Particle Mapping Using Magnetoelectric Sensors.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Superparamagnetic iron-oxide nanoparticles can be used in medical applications like vascular or targeted imaging. Magnetic particle imaging (MPI) is a promising tomographic imaging technique that allows visualizing the 3D nanoparticle distribution concentration in a non-invasive manner. The two main strengths of MPI are high temporal resolution and high sensitivity. While the first has been proven in the assessment of dynamic processes like cardiac imaging, it is unknown how far the detection limit of MPI can be lowered. Within this work, we will present a highly sensitive gradiometric receive-coil unit combined with a noise-matching network tailored for the imaging of mice. The setup is capable of detecting 5 ng of iron in-vitro with an acquisition time of 2.14 sec. In terms of iron concentration we are able to detect 156 μg/L marking the lowest value that has been reported for an MPI scanner so far. In-vivo MPI mouse images of a 512 ng bolus and a 21.5 ms acquisition time allow for capturing the flow of an intravenously injected tracer through the heart of a mouse. Since it has been rather difficult to compare detection limits across MPI publications we propose guidelines to improve the comparability of future MPI studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.