Evidence map›Paper›PMID 28761025›Full record

ArticleAnnals of Saudi medicine

Eleven-year review of data on Pap smears in Saudi Arabia: We need more focus on glandular abnormalities!

Haitham Nasser, Mohammad AlAyyaf, Azza Atallah, Mohammad Aminulislam, Lubna Rizwan, Abdulsalam Aodah, Yasser Alkahtani, Haifa Alshammari, Ahmed Alsayed, Susan Szpunar

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Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Haitham NasserDr. Haitham Nasser, Department of Histopathology,, King Saud Medical City,, Riyadh 11575, T: +966-11-4355555;, F: +966-11-4353045, samnasser78@gmail.com, ORCID: http://orcid.org/0000-0001-5939-1542.
Mohammad AlAyyaf
Azza Atallah
Mohammad Aminulislam
Lubna Rizwan
Abdulsalam Aodah
Yasser Alkahtani
Haifa Alshammari
Ahmed Alsayed
Susan Szpunar
King Saud Medical City · SASt. John Hospital & Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe reviewed data from Saudi Arabia on epithelial cell abnormalities (ECA) detected by Pap smear after noticing a slight increase in the incidence of cervical glandular abnormalities in our regional laboratory in recent years.

objectiveClarify data on adenocarcinoma (ADCA) on Pap smears in Saudi Arabia.

designDescriptive, retrospective study. SETTINGS: Regional laboratory, Riyadh. PATIENTS AND

methodsWe reviewed all Pap smears of adult females between 2006 and 2016 and compared our data with previously published results from Saudi Arabia. MAIN OUTCOME MEASURE(S): Descriptive data on ECAs.

resultsAmong 19759 cases, atypical squamous cell of undetermined significance (ASC-US) was the most prevalent ECA (1.16%). ADCA occurred more than squamous cell carcinoma (SCC). In a comparison of published data before 2014 and after 2014 (including ours), there was a significant rise in ADCA (28 vs 48 cases; P=.004) with a significant drop in SCC, high-grade squamous intraepithelial lesions (HSIL) and low-grade squamous intraepithelial lesions (LSIL) (P < .0001, .004, and < .0001, respectively).

conclusionWe recommend that pathologists and cytotechnologists be vigilant in screening Pap smears in our population, particularly for glandular abnormalities. We also recommend use of Pap smears in the initial workup of women with suspected gynecological abnormalities, regardless of evolutions in HPV testing. LIMITATIONS: The pooling of data instead of analyzing by study year.

Indexed as

AdenocarcinomaAdultAgedAtypical Squamous Cells of the CervixCarcinoma, Squamous CellFemaleHumansIncidenceMiddle AgedPapanicolaou TestPrevalenceRetrospective StudiesSaudi ArabiaSquamous Intraepithelial Lesions of the CervixUterine Cervical DysplasiaUterine Cervical Neoplasms

Identifiers

PMID28761025
PMCPMC6150586
OpenAlexW2744706550

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.