Evidence map›Paper›PMID 28760979›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.

David González-Bullón, Kepa B Uribe, César Martín, Helena Ostolaza

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. How Do Biomolecules Cross the Cell Membrane?Accounts of chemical research · 2022
    Article
  4. Article
  5. RTX-Toxins.Toxins · 2020
    Article
  6. Review
  7. Review
  8. Review
  9. Membrane Permeabilization byBiomolecules · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Bioengineering ofToxins · 2018
    Review
  14. Toxins · 2018
    Article
  15. Review
  16. Phospholipase A activity of adenylate cyclase toxin?Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  17. Reply to Masin et al: To be or not to be a phospholipase A.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

David González-BullónBiofisika Institute (UPV/EHU, CSIC), University of Basque Country, 48080 Bilbao, Spain.
Kepa B UribeBiofisika Institute (UPV/EHU, CSIC), University of Basque Country, 48080 Bilbao, Spain.
César MartínBiofisika Institute (UPV/EHU, CSIC), University of Basque Country, 48080 Bilbao, Spain.
Helena OstolazaBiofisika Institute (UPV/EHU, CSIC), University of Basque Country, 48080 Bilbao, Spain; elenaamaya.ostolaza@ehu.es.ORCID 0000-0002-2346-5228
Institut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenylate cyclase toxin (ACT or CyaA) plays a crucial role in respiratory tract colonization and virulence of the whooping cough causative bacterium

Indexed as

Adenylate Cyclase ToxinAmino Acid SequenceAnimalsBordetella pertussisCatalytic DomainCell LineCell MembraneCyclic AMPHumansMacrophagesMembrane LipidsMicePhospholipases AProtein TransportSequence Homology, Amino AcidWhooping CoughAdenylate Cyclase ToxinCyclic AMPMembrane LipidsPhospholipases Abacterial toxinsbiological membranesmembrane remodelingprotein translocationRTX toxin family

Identifiers

PMID28760979
PMCPMC5565420
OpenAlexW2740620180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.