Evidence map›Paper›PMID 28760884›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

HIV-1 Infection Is Associated with Depletion and Functional Impairment of

Cheryl L Day, Deborah A Abrahams, Levelle D Harris, Michele van Rooyen, Lynnett Stone, Marwou de Kock, Willem A Hanekom

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India.Journal of clinical tuberculosis and other mycobacterial diseases · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Specific immune response toFrontiers in immunology · 2024
    Article
  13. Review
  14. Evaluation of ESAT6-CFP10 Skin Test forJournal of clinical microbiology · 2023
    Article
  15. Evaluation of theFrontiers in cellular and infection microbiology · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. The Role of CD4Frontiers in public health · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Cheryl L DayDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30329; cday@emory.edu.
Deborah A AbrahamsSouth African Tuberculosis Vaccine Initiative and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa.
Levelle D HarrisEmory Vaccine Center, Emory University, Atlanta, GA 30329; and.
Michele van RooyenSouth African Tuberculosis Vaccine Initiative and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa.
Lynnett StoneSouth African Tuberculosis Vaccine Initiative and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa.
Marwou de KockSouth African Tuberculosis Vaccine Initiative and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa.
Willem A HanekomSouth African Tuberculosis Vaccine Initiative and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa.
South African Tuberculosis Vaccine Initiative · ZAEmory University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Mechanisms of Immune Regulation in Mycobacterium Tuberculosis InfectionR01AI083156 · NIAID · UNIVERSITY OF CAPE TOWN · PI DAY, CHERYL LIANE · 2009 to 2012
$415k
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI083156NIGMS NIH HHS T32 GM008169NIH HHS P51 OD011132
6 · The paper itself

Abstract

Coinfection with HIV is the single greatest risk factor for reactivation of latent

Indexed as

Virus LatencyAdolescentAdultAntigens, BacterialApoptosisCD4-Positive T-LymphocytesCell ProliferationCells, CulturedCoinfectionFemaleHIV-1HIV InfectionsHumansImmunophenotypingInterferon-gammaInterleukin-2Antigens, BacterialInterferon-gammaInterleukin-2

Identifiers

PMID28760884
PMCPMC5624214
OpenAlexW2740017267

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.