Evidence map›Paper›PMID 28760883›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Cutting Edge: NKG2D Signaling Enhances NK Cell Responses but Alone Is Insufficient To Drive Expansion during Mouse Cytomegalovirus Infection.

Tsukasa Nabekura, Dagmar Gotthardt, Kouta Niizuma, Tihana Trsan, Tina Jenus, Stipan Jonjic, Lewis L Lanier

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  7. MHC class Ib-restricted CD8Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Virus-specific NK cell memory.The Journal of experimental medicine · 2021
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Memory responses of natural killer cells.Seminars in immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Tsukasa NabekuraDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143.
Dagmar GotthardtDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143.ORCID 0000-0002-8416-1236
Kouta NiizumaDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143.
Tihana TrsanDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia.ORCID 0000-0002-7549-2885
Tina JenusDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia.ORCID 0000-0002-1995-9620
Stipan JonjicDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia.
Lewis L LanierDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143; Lewis.Lanier@ucsf.edu.ORCID 0000-0003-1308-3952
University of Rijeka · HRUniversity of California, San Francisco · USUniversity of Tsukuba · JP

Funding

NK MemoryR01AI068129 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANIER, LEWIS LEE · 2006 to 2020
$6.0M
NK and T Cell Costimulation by NKG2D/DAP10R37AI066897 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANIER, LEWIS LEE · 2006 to 2015
$3.8M
European Research Council 322693NIAID NIH HHS R01 AI068129NIAID NIH HHS R37 AI066897
6 · The paper itself

Abstract

NK cells play a critical role in host defense against viruses. In this study, we investigated the role of NKG2D in the expansion of NK cells after mouse CMV (MCMV) infection. Wild-type and NKG2D-deficient (

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCell ProliferationCells, CulturedHerpesviridae InfectionsImmunity, InnateKiller Cells, NaturalLymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutMuromegalovirusNK Cell Lectin-Like Receptor Subfamily ANK Cell Lectin-Like Receptor Subfamily KProtein BindingReceptors, ImmunologicAdaptor Proteins, Signal TransducingHcst protein, mouseKlra8 protein, mouseNK Cell Lectin-Like Receptor Subfamily ANK Cell Lectin-Like Receptor Subfamily KReceptors, ImmunologicTyrobp protein, mouse

Identifiers

PMID28760883
PMCPMC5567695
OpenAlexW2739505325

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.