Evidence map›Paper›PMID 28760859›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Sound-Evoked Activity Influences Myelination of Brainstem Axons in the Trapezoid Body.

James L Sinclair, Matthew J Fischl, Olga Alexandrova, Martin Heβ, Benedikt Grothe, Christian Leibold, Conny Kopp-Scheinpflug

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Plasticity of Myelination.Advances in neurobiology · 2025
    Review
  14. Article
  15. Oligodendrocytes: Myelination, Plasticity, and Axonal Support.Cold Spring Harbor perspectives in biology · 2024
    Review
  16. Review
  17. Dynamics of mature myelin.Nature neuroscience · 2024
    Review
  18. Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

James L SinclairDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany.
Matthew J FischlDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany.
Olga AlexandrovaDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany.
Martin HeβDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany.
Benedikt GrotheDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany.
Christian LeiboldDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany.ORCID 0000-0002-4859-8000
Conny Kopp-ScheinpflugDivision of Neurobiology, Department Biology II, Ludwig-Maximilians-University Munich, 82152 Planegg-Martinsried, Germany cks@bio.lmu.de.
Ludwig-Maximilians-Universität München · DEMax Planck Institute of Neurobiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasticity of myelination represents a mechanism to tune the flow of information by balancing functional requirements with metabolic and spatial constraints. The auditory system is heavily myelinated and operates at the upper limits of action potential generation frequency and speed observed in the mammalian CNS. This study aimed to characterize the development of myelin within the trapezoid body, a central auditory fiber tract, and determine the influence sensory experience has on this process in mice of both sexes. We find that

Indexed as

Acoustic StimulationAction PotentialsAnimalsAuditory PathwaysAxonsBrain StemEvoked Potentials, AuditoryFemaleMaleMiceMice, Inbred CBANerve Fibers, MyelinatedOrgan Culture TechniquesSoundTrapezoid BodyABRauditory brainstemaxonal conduction speedcalyx of HeldMNTBmyelination

Identifiers

PMID28760859
PMCPMC5566870
OpenAlexW2742134786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.