Evidence map›Paper›PMID 28760823›Full record

ArticleThe Journal of biological chemistry2017

Ascorbate peroxidase proximity labeling coupled with biochemical fractionation identifies promoters of endoplasmic reticulum-mitochondrial contacts.

Il-Taeg Cho, Guillaume Adelmant, Youngshin Lim, Jarrod A Marto, Ginam Cho, Jeffrey A Golden

Abstract readValidation Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

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  15. Imaging and proteomics toolkits for studying organelle contact sites.Frontiers in cell and developmental biology · 2024
    Review
  16. Article
  17. Review
  18. Assessing Peroxisomal Protein Interaction by Immunoprecipitation.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  19. Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Il-Taeg ChoFrom the Department of Pathology, Brigham and Women's Hospital, and.
Guillaume Adelmantthe Departments of Cancer Biology and Pathology, Blais Proteomics Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115.
Youngshin LimFrom the Department of Pathology, Brigham and Women's Hospital, and.
Jarrod A MartoFrom the Department of Pathology, Brigham and Women's Hospital, and.
Ginam ChoFrom the Department of Pathology, Brigham and Women's Hospital, and gpcho@bwh.harvard.edu.
Jeffrey A GoldenFrom the Department of Pathology, Brigham and Women's Hospital, and jagolden@bwh.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To maintain cellular homeostasis, subcellular organelles communicate with each other and form physical and functional networks through membrane contact sites coupled by protein tethers. In particular, endoplasmic reticulum (ER)-mitochondrial contacts (EMC) regulate diverse cellular activities such as metabolite exchange (Ca

Indexed as

Ascorbate PeroxidasesEndoplasmic ReticulumGenetic Complementation TestHEK293 CellsHumansIndicators and ReagentsIsotope LabelingLuciferases, RenillaMitochondriaNerve Tissue ProteinsPeptide FragmentsPilot ProjectsProtein EngineeringProtein Interaction MappingRecombinant ProteinsAscorbate PeroxidasesIndicators and ReagentsLuciferases, RenillaNerve Tissue ProteinsPeptide FragmentsRecombinant ProteinsRTN1 protein, humanascorbate peroxidaseendoplasmic reticulum (ER)endoplasmic reticulum stress (ER stress)ER-Mitochondria contactsinterorganelle communicationmitochondrianeurodegenerative diseasereticulonsignaling

Identifiers

PMID28760823
PMCPMC5625067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.