Evidence map›Paper›PMID 28760789›Full record

SynthesisBMJ open2017

Guidelines for the symptomatic management of fever in children: systematic review of the literature and quality appraisal with AGREE II.

Elena Chiappini, Barbara Bortone, Luisa Galli, Maurizio de Martino

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Nutritional Risk Screening Recommendations for Critically Ill Patients: A Meta-Research Study and Quality Appraisal of Clinical Guidelines.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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  11. Review
  12. Quality Appraisal of Telerehabilitation Guidelines: A Systematic Review.International journal of telemedicine and applications · 2026
    Review
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  18. Article
  19. Observational
  20. Effect of ibuprofen on amelogenesis in Wistar rats.Journal of applied oral science : revista FOB · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elena ChiappiniDepartment of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.
Barbara BortoneDepartment of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.
Luisa GalliDepartment of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.
Maurizio de MartinoDepartment of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral societies have produced and disseminated clinical practice guidelines (CPGs) for the symptomatic management of fever in children. However, to date, the quality of such guidelines has not been appraised.

objectiveTo identify and evaluate guidelines for the symptomatic management of fever in children.

methodsThe research was conducted using PubMed, guideline websites, and Google (January 2010 to July 2016). The quality of the CPGs was independently assessed by two assessors using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) instrument, and specific recommendations in guidelines were summarised and evaluated. Domain scores were considered of sufficient quality when >60% and of good quality when >80%.

resultsSeven guidelines were retrieved. The median score for the scope and purpose domain was 85.3% (range 66.6-100%). The median score for the stakeholder involvement domain was 57.5% (range 33.3-83.3%) and four guidelines scored >60%. The median score for the rigour of development domain was 52.0% (range 14.6-98.9%), and only three guidelines scored >60%. The median score for the clarity of presentation domain was 80.9% (range 50.0-94.4%). The median score for the applicability domain was 39.3% (8.3-100%). Only one guideline scored >60%. The median score for the editorial independence domain was 48.84% (0-91.6%); only three guidelines scored >60%.

conclusionMost guidelines were recommended for use even if with modification, especially in the methodology, the applicability and the editorial independence domains. Our results could help improve reporting of future guidelines, and affect the selection and use of guidelines in clinical practice.

Indexed as

ChildFeverHumansPediatricsPractice Guidelines as TopicSocieties, MedicalantipyreticsChildrenfeverguidelines

Identifiers

PMID28760789
PMCPMC5642818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.