ArticleJournal of psychiatric research2017
A comprehensive model of predictors of persistence and recurrence in adults with major depression: Results from a national 3-year prospective study.
Article in Journal of psychiatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- The impact of fibroid treatments on quality of life and mental health: a systematic review.Fertility and sterility · 2024Pooled it
- Anxiety, Depression and Quality of Life-A Systematic Review of Evidence from Longitudinal Observational Studies.International journal of environmental research and public health · 2021Pooled it
- Analysis of the Components of a Cognitive-Behavioral Intervention for the prevention of Depression Administered via Conference Call to Nonprofessional Caregivers: A Randomized Controlled Trial.International journal of environmental research and public health · 2020Trial
- Prevalence and Clinical Correlates of Suicide Attempts Among Young Patients With Major Depressive Disorder With Subclinical Hypothyroidism: A Cross-Sectional Study.Brain and behavior · 2026Article
- The Onset, Course and Co-Occurrence of Depressive and Anxiety Disorders Over a 9-Year Period in the General Population.International journal of methods in psychiatric research · 2026Article
- Reinitiation of antidepressant pharmacotherapy among patients discharged from the hospital: A population-based cohort study.PLOS mental health · 2026Article
- Modeling effect: How treatment intensity and duration impact depression recurrence.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Nicotine dependence and incident psychiatric disorders: prospective evidence from US national study.Molecular psychiatry · 2025Article
- Risk factors of chronic course of anxiety and depressive disorders: a 3-year longitudinal study in the general population.Social psychiatry and psychiatric epidemiology · 2024Article
- Discriminative capacity of the Spanish version of the Inventory of Depression and Anxiety Symptoms-II (IDAS-II) for detecting DMS-5 specific disorders and poor quality of life in a clinical sample.Health and quality of life outcomes · 2024Article
- A Complex Relationship between Quality of Life, Anxiety, and Depression among General Population during Second Year of COVID-19 Pandemic: A Population-Based Study.Journal of clinical medicine · 2024Article
- Metabolic features of treatment-refractory major depressive disorder with suicidal ideation.Translational psychiatry · 2023Article
- Psychiatric symptoms and mortality in older adults with major psychiatric disorders: results from a multicenter study.European archives of psychiatry and clinical neuroscience · 2023Article
- Alcohol use as a predictor of the course of major depressive disorder: a prospective population-based study.Epidemiology and psychiatric sciences · 2023Article
- The prevalence of anxiety and its key influencing factors among the elderly in China.Frontiers in psychiatry · 2023Article
- The Effectiveness of an Intensive Inpatient Psychotherapy Program for Chronic Depression: A naturalistic comparison with wait list.BMC psychiatry · 2022Article
- A comprehensive model of predictors of quality of life in older adults with schizophrenia: results from the CSA study.Social psychiatry and psychiatric epidemiology · 2021Article
- Family history of depression is associated with alterations in task-dependent connectivity between the cerebellum and ventromedial prefrontal cortex.Depression and anxiety · 2021Article
- Metabolic features of recurrent major depressive disorder in remission, and the risk of future recurrence.Translational psychiatry · 2021Article
- Psychiatric symptoms and quality of life in older adults with schizophrenia spectrum disorder: results from a multicenter study.European archives of psychiatry and clinical neuroscience · 2020Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
Identifying predictors of persistence and recurrence of depression in individuals with a major depressive episode (MDE) poses a critical challenge for clinicians and researchers. We develop using a nationally representative sample, the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; N = 34,653), a comprehensive model of the 3-year risk of persistence and recurrence in individuals with MDE at baseline. We used structural equation modeling to examine simultaneously the effects of four broad groups of clinical factors on the risk of MDE persistence and recurrence: 1) severity of depressive illness, 2) severity of mental and physical comorbidity, 3) sociodemographic characteristics and 4) treatment-seeking behavior. Approximately 16% and 21% of the 2587 participants with an MDE at baseline had a persistent MDE and a new MDE during the 3-year follow-up period, respectively. Most independent predictors were common for both persistence and recurrence and included markers for the severity of the depressive illness at baseline (as measured by higher levels on the general depressive symptom dimension, lower mental component summary scores, prior suicide attempts, younger age at onset of depression and greater number of MDEs), the severity of comorbidities (as measured by higher levels on dimensions of psychopathology and lower physical component summary scores) and a failure to seek treatment for MDE at baseline. This population-based model highlights strategies that may improve the course of MDE, including the need to develop interventions that target multiple psychiatric disorders and promotion of treatment seeking to increase access to timely mental health care.
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