ArticlePLoS neglected tropical diseases2017
Control of chronic Strongyloides stercoralis infection in an endemic community may be possible by pharmacological means alone: Results of a three-year cohort study.
Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Strongyloidiasis Diagnosed by ELISA in Brussels: A Bicentric Retrospective Study.Microorganisms · 2026Article
- Cost-Effectiveness of Treatment for Canine Parasites in Remote Indigenous Communities.EcoHealth · 2025Article
- Evaluating the effectiveness and sustainability of a primary healthcare strategy to reduce the prevalence of strongyloidiasis in endemically infected Indigenous communities in Northern Australia.PLoS neglected tropical diseases · 2025Article
- Review
- The Association between Diabetes and Human T-Cell Leukaemia Virus Type-1 (HTLV-1) withInternational journal of environmental research and public health · 2022Article
- Seropositivity and geographical distribution of Strongyloides stercoralis in Australia: A study of pathology laboratory data from 2012-2016.PLoS neglected tropical diseases · 2021Article
- A Cross-Sectional Study of Seroprevalence of Strongyloidiasis in Pregnant Women (Peruvian Amazon Basin).Pathogens (Basel, Switzerland) · 2020Article
- Integrating testing for chronic strongyloidiasis within the Indigenous adult preventive health assessment system in endemic communities in the Northern Territory, Australia: An intervention study.PLoS neglected tropical diseases · 2020Article
- Progress towards the Control of Strongyloidiasis in Tropical Australia?The American journal of tropical medicine and hygiene · 2020Article
- Rapid Progress toward Elimination of Strongyloidiasis in North Queensland, Tropical Australia, 2000-2018.The American journal of tropical medicine and hygiene · 2020Article
- Environmental health in Australia: overlooked and underrated.Journal of public health (Oxford, England) · 2019Article
- In vitro ovicidal and larvicidal activity of Carica papaya seed hexane extract against Strongyloides venezuelensis.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- Prevalence of Strongyloides stercoralis infection and hyperinfection syndrome among renal allograft recipients in Central Europe.Scientific reports · 2018Article
- Exotic Parasite Threats to Australia's Biosecurity-Trade, Health, and Conservation.Tropical medicine and infectious disease · 2018Review
- Paediatric Strongyloidiasis in Central Australia.Tropical medicine and infectious disease · 2018Article
- Soil-Transmitted Helminths in Tropical Australia and Asia.Tropical medicine and infectious disease · 2017Review
- Genetic Diversity ofIranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the effect of treatment with ivermectin on the prevalence of S. stercoralis infection in an Australian Aboriginal population over a three year period, and to assess the validity of using a lower ELISA cut-off in diagnosis.
methodsA three-year cohort study of 259 adult Australian Aboriginals living in a remote community in northern Australia. S stercoralis infection was diagnosed using commercial ELISA testing, and employed a lower threshold for treatment than that recommended. Follow up was conducted at 6 months and 3 years following ivermectin treatment.
findingsTreatment with ivermectin was highly effective and resulted in a sustained fall in the prevalence of infection in the study group (Initial prevalence 35.3%, 3 year prevalence 5.8%, McNemar's chi2 = 56.5, p<0.001). Results of treatment suggested use of a lower ELISA threshold for treatment was valid in this setting. Follow up identified a small group of subjects with persistently positive ELISA serology despite repeated treatment.
interpretationControl of S. stercoralis infection in this cohort appears to be feasible using pharmacological treatment alone.
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Registered trials
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