Evidence map›Paper›PMID 28759396›Full record

Trial reportPediatrics2017

Pictograms, Units and Dosing Tools, and Parent Medication Errors: A Randomized Study.

H Shonna Yin, Ruth M Parker, Lee M Sanders, Alan Mendelsohn, Benard P Dreyer, Stacy Cooper Bailey, Deesha A Patel, Jessica J Jimenez, Kwang-Youn A Kim, Kara Jacobson and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Preventing Medication Errors in Paediatrics: A Narrative Review.Clinical medicine insights. Pediatrics · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Extemporaneous preparation of rifampicin granules from capsules to improve usability.European journal of hospital pharmacy : science and practice · 2023
    Article
  16. Article
  17. Pharmacist-Led Discharge Transitions of Care Interventions for Pediatric Patients: A Narrative Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

H Shonna YinDepartment of Pediatrics, New York University School of Medicine, NYC Health + Hospitals/Bellevue, New York, New York; yinh02@med.nyu.edu.
Ruth M ParkerDepartments of Medicine and.
Lee M SandersDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Alan MendelsohnDepartment of Pediatrics, New York University School of Medicine, NYC Health + Hospitals/Bellevue, New York, New York.
Benard P DreyerDepartment of Pediatrics, New York University School of Medicine, NYC Health + Hospitals/Bellevue, New York, New York.
Stacy Cooper BaileyDivision of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina.
Deesha A PatelDivision of General Internal Medicine and Geriatrics and.
Jessica J JimenezDepartment of Pediatrics, New York University School of Medicine, NYC Health + Hospitals/Bellevue, New York, New York.
Kwang-Youn A KimDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Kara JacobsonRollins School of Public Health, Emory University, Atlanta, Georgia.
Michelle C J SmithDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Laurie HedlundDivision of General Internal Medicine and Geriatrics and.
Nicole MeyersDepartment of Pediatrics, New York University School of Medicine, NYC Health + Hospitals/Bellevue, New York, New York.
Terri McFaddenPediatrics, Emory University School of Medicine, Atlanta, Georgia; and.
Michael S WolfDivision of General Internal Medicine and Geriatrics and.

Funding

Promoting Safe Use of Pediatric Liquid Medications: A Health Literacy ApproachR01HD070864 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI YIN, HSIANG · 2012 to 2015
$2.6M
NICHD NIH HHS R01 HD070864
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPoorly designed labels and dosing tools contribute to dosing errors. We examined the degree to which errors could be reduced with pictographic diagrams, milliliter-only units, and provision of tools more closely matched to prescribed volumes.

methodsThis study involved a randomized controlled experiment in 3 pediatric clinics. English- and Spanish-speaking parents (

resultsWe found that 83.5% of parents made ≥1 dosing error (overdosing was present in 12.1% of errors) and 29.3% of parents made ≥1 large error (>2× dose). The greatest impact on errors resulted from the provision of tools more closely matched to prescribed dose volumes. For the 2-mL dose, the fewest errors were seen with the 5-mL syringe (5- vs 10-mL syringe: adjusted odds ratio [aOR] = 0.3 [95% confidence interval: 0.2-0.4]; cup versus 10-mL syringe: aOR = 7.5 [5.7-10.0]). For the 7.5-mL dose, the fewest errors were with the 10-mL syringe, which did not necessitate measurement of multiple instrument-fulls (5- vs 10-mL syringe: aOR = 4.0 [3.0-5.4]; cup versus 10-mL syringe: aOR = 2.1 [1.5-2.9]). Milliliter/teaspoon was associated with more errors than milliliter-only (aOR = 1.3 [1.05-1.6]). Parents who received text only (versus text and pictogram) instructions or milliliter/teaspoon (versus milliliter-only) labels and tools made more large errors (aOR = 1.9 [1.1-3.3], aOR = 2.5 [1.4-4.6], respectively).

conclusionsProvision of dosing tools more closely matched to prescribed dose volumes is an especially promising strategy for reducing pediatric dosing errors.

Indexed as

Drug Dosage CalculationsChildChild, PreschoolDrug LabelingFemaleHealth LiteracyHumansLanguageMaleMedication ErrorsParents

Identifiers

PMID28759396
PMCPMC5495522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.