ArticleNature neuroscience2017
Functional dissection of signal and noise in MT and LIP during decision-making.
Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed.
- Distinct sources of decision-related signals in visual cortex are represented in different local field potential bands.PLoS biology · 2026Article
- Regime shift detection and neurocomputational substrates for under and overreactions to change.eLife · 2026Article
- Mechanisms of Visuomotor Interception.Brain sciences · 2026Review
- A Population Coupling Model Identifies Reduced Propagation from V1 to Higher Visual Areas During Locomotion.bioRxiv : the preprint server for biology · 2026Article
- Principles of cortical interactions in modular recurrent networks.bioRxiv : the preprint server for biology · 2026Article
- Primate-informed neural network for visual decision-making.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Brain-wide coordination of internal signals during decision-making.bioRxiv : the preprint server for biology · 2025Article
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- Nonlinear feedback modulation contributes to the optimization of flexible decision-making.eLife · 2025Article
- A solvable neural circuit model revealing the dynamical principle of non-optimal temporal weighting in perceptual decision making.Journal of computational neuroscience · 2025Article
- People display consistent recency and primacy effects in behavior and neural activity across perceptual and value-based judgments.Cognitive, affective & behavioral neuroscience · 2025Article
- Confirmation bias through selective readout of information encoded in human parietal cortex.Nature communications · 2025Article
- Distinct neural population code and causal roles of primate caudate nucleus in multimodal decision-making.Nature communications · 2025Article
- Confirmation Bias through Selective Readout of Information Encoded in Human Parietal Cortex.bioRxiv : the preprint server for biology · 2025Article
- Disentangling sources of variability in decision-making.Nature reviews. Neuroscience · 2025Review
- Early versus late noise differentially enhances or degrades context-dependent choice.Nature communications · 2025Article
- Identifying interactions across brain areas while accounting for individual-neuron dynamics with a Transformer-based variational autoencoder.Advances in neural information processing systems · 2025Article
- Failure to replicate the Aubert-Fleischl effect.PloS one · 2025Article
- Thalamocortical interactions shape hierarchical neural variability during stimulus perception.iScience · 2024Article
12 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
During perceptual decision-making, responses in the middle temporal (MT) and lateral intraparietal (LIP) areas appear to map onto theoretically defined quantities, with MT representing instantaneous motion evidence and LIP reflecting the accumulated evidence. However, several aspects of the transformation between the two areas have not been empirically tested. We therefore performed multistage systems identification analyses of the simultaneous activity of MT and LIP during individual decisions. We found that monkeys based their choices on evidence presented in early epochs of the motion stimulus and that substantial early weighting of motion was present in MT responses. LIP responses recapitulated MT early weighting and contained a choice-dependent buildup that was distinguishable from motion integration. Furthermore, trial-by-trial variability in LIP did not depend on MT activity. These results identify important deviations from idealizations of MT and LIP and motivate inquiry into sensorimotor computations that may intervene between MT and LIP.
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