ReviewJournal of clinical medicine2017
Ultrasound for Early Detection of Joint Disease in Patients with Hemophilic Arthropathy.
Review in Journal of clinical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Evolution of Hemophilia Management in Italy: Results from a Delphi Consensus Study.Journal of clinical medicine · 2026Article
- Hemophilia in the Era of Advanced Therapies: Structural Monitoring, the Role of Musculoskeletal Ultrasound, and a Proposed Multidisciplinary Care Model-A Structured Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Joint health status in people with moderate hemophilia A: a cross-sectional multicenter study.Research and practice in thrombosis and haemostasis · 2025Article
- Predictive parameters for spontaneous joint bleeding during emicizumab prophylaxis.Blood advances · 2024Article
- Ultrasound evaluation of hemophilic arthropathy: a proposal of definitions in a changing landscape.Research and practice in thrombosis and haemostasis · 2024Article
- Comparison of joint status using ultrasound assessments and Haemophilia Joint Health Score 2.1 in children with haemophilia.Frontiers in medicine · 2023Article
- Haemophilia, state of the art and new therapeutic opportunities, a regulatory perspective.British journal of clinical pharmacology · 2021Review
- Musculoskeletal ultrasound in hemophilia: Results and recommendations from a global survey and consensus meeting.Research and practice in thrombosis and haemostasis · 2021Article
- Impact of the HEAD-US Scoring System for Observing the Protective Effect of Prophylaxis in Hemophilia Patients: A Prospective, Multicenter, Observational StudyTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021Observational
- The Progression of Hemophilic Arthropathy: The Role of Biomarkers.International journal of molecular sciences · 2020Review
- Pathophysiological Role of Synovitis in Hemophilic Arthropathy Development: A Two-Hit Hypothesis.Frontiers in physiology · 2020Review
- Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery.International journal of environmental research and public health · 2019Review
- Merging into the mainstream: the evolution of the role of point-of-care musculoskeletal ultrasound in hemophilia.F1000Research · 2019Review
- Article
- [HEAD-US-C quantitative ultrasound assessment scale in evaluation of joint damage in patients with moderate or severe hemophilia A received on-demand versus prophylaxis replacement therapy].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2018Article
- Point-of-care Ultrasonography in Orthopedic Management of Hemophilia: Multiple Uses of an Effective Tool.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2018Review
- [Clinical application and optimization of HEAD-US quantitative ultrasound assessment scale for hemophilic arthropathy].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2018Article
- Use of the Multidimensional Haemophilia Pain Questionnaire (MHPQ) in Patients With Severe Haemophilia A Treated With Emicizumab: A Pilot Cross-Sectional, Single-Centre Study.Haemophilia : the official journal of the World Federation of HemophiliaArticle
- Concurrence of Pigmented Villonodular Synovitis with Calcium Pyrophosphate Deposition in a Postacute Stroke Patient.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Joint bleeding represents the most commonly reported type of hemorrhage in patients affected by hemophilia. Although the widespread use of prophylaxis has been able to significantly reduce the onset of arthropathy, it has been shown that a non-negligible percentage of patients develop degenerative changes in their joints despite this type of treatment. Thus, periodic monitoring of the joint status in hemophilia patients has been recommended to identify early arthropathic changes and prevent the development or progression of hemophilic arthropathy. Ultrasound (US) has proven able to detect and quantify the most relevant biomarkers of disease activity (i.e., joint effusion and synovial hypertrophy) and degenerative damages (i.e., osteo-chondral changes) by means of scoring scales of increasing disease severity. In the present review, we have detailed major literature evidence about the use of US to assess joint status in hemophilia patients, focusing on signs of disease activity and degenerative damages. In particular, we have discussed recent evidence about "point-of-care" use patients with hemophilia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.