Trial reportNutrients2017
A Single Day of Excessive Dietary Fat Intake Reduces Whole-Body Insulin Sensitivity: The Metabolic Consequence of Binge Eating.
Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Associations Between Microbial Depletion and Autonomic Dysregulation in Binge-Eating Disorder.The International journal of eating disorders · 2026Article
- Article
- Review
- Adult users of a digital binge-eating intervention wanted adaptations for type 2 diabetes: Qualitative study of post-intervention preferences.Research square · 2026Article
- Nutritional considerations for athletes with diabetes: optimizing performance and glycemic control.Frontiers in nutrition · 2026Review
- Association between tendency to overeat and the incidence of prediabetes: Aichi Workers' Cohort Study.Environmental health and preventive medicine · 2026Article
- The Intersection of Diabetes and Eating Disorders: Prevention, Screening, Diagnosis, and Management.American journal of lifestyle medicine · 2025Review
- Assessment of Eating Attitude and Psychiatric Parameters in Patients with Acne Vulgaris.Dermatology practical & conceptual · 2025Article
- Disordered eating and cardiometabolic risk factors in Chinese women: evidence from the China Health and Nutrition Survey.The British journal of nutrition · 2024Article
- Associations between food insecurity and diabetes risk factors in US adolescents in the National Health and Nutrition Examination Survey (NHANES) 2007-2016.Public health nutrition · 2024Article
- Short-term high-fat and high-carb diet effects on glucose metabolism and hedonic regulation in young healthy men.Frontiers in nutrition · 2024Article
- The role of Neurochemicals, Stress Hormones and Immune System in the Positive Feedback Loops between Diabetes, Obesity and Depression.Frontiers in endocrinology · 2023Review
- Efficacy of the holistic, psychonutritional approach ofJournal of diabetes and metabolic disorders · 2022Review
- Managing type 2 diabetes or prediabetes and binge eating disorder: a qualitative study of patients' perceptions and lived experiences.Journal of eating disorders · 2022Article
- Dietary Energy Partition: The Central Role of Glucose.International journal of molecular sciences · 2020Review
- Binge Eating Disorder in Patients with Type 2 Diabetes: Diagnostic and Management Challenges.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Review
- Binge eating in patients with polycystic ovary syndrome: prevalence, causes, and management strategies.Neuropsychiatric disease and treatment · 2019Review
- Binge eating disorder and night eating syndrome in adults with type 2 diabetes: a systematic review.Journal of eating disorders · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Consuming excessive amounts of energy as dietary fat for several days or weeks can impair glycemic control and reduce insulin sensitivity in healthy adults. However, individuals who demonstrate binge eating behavior overconsume for much shorter periods of time; the metabolic consequences of such behavior remain unknown. The aim of this study was to determine the effect of a single day of high-fat overfeeding on whole-body insulin sensitivity. Fifteen young, healthy adults underwent an oral glucose tolerance test before and after consuming a high-fat (68% of total energy), high-energy (78% greater than daily requirements) diet for one day. Fasting and postprandial plasma concentrations of glucose, insulin, non-esterified fatty acids, and triglyceride were measured and the Matsuda insulin sensitivity index was calculated. One day of high-fat overfeeding increased postprandial glucose area under the curve (AUC) by 17.1% (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.