Evidence map›Paper›PMID 28758329›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2018

Kidney allograft offers: Predictors of turndown and the impact of late organ acceptance on allograft survival.

J B Cohen, J Shults, D S Goldberg, P L Abt, D L Sawinski, P P Reese

Open access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Optimizing kidney allocation: challenges and solutions.Current opinion in organ transplantation · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Kidney nonprocurement in solid organ donors in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Leveraging marginal structural modeling with Cox regression to assess the survival benefit of accepting vs declining kidney allograft offers.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019
    Article
  14. Bariatric surgery before and after kidney transplantation: long-term weight loss and allograft outcomes.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Article
  15. Article
  16. Inferior long-term allograft and patient outcomes among recipients of offspring living donor kidneys.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
  17. Turn down for what? Patient outcomes associated with declining increased infectious risk kidneys.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J B CohenRenal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, USA.
J ShultsCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA.
D S GoldbergCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA.
P L AbtDepartment of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
D L SawinskiRenal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, USA.
P P ReeseRenal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · US

Funding

Management of hypertension in obesity: Antihypertensive class effects, blood pressure control, and renal and cardiac outcomesK23HL133843 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI COHEN, JORDANA B. · 2016 to 2020
$945k
NHLBI NIH HHS K23 HL133843
6 · The paper itself

Abstract

There is growing interest in understanding patterns of organ acceptance and reducing discard. Little is known about how donor factors, timing of procurement, and geographic location affect organ offer decisions. We performed a retrospective cohort study of 47 563 deceased donor kidney match-runs from 2007 to 2013. Several characteristics unrelated to allograft quality were independently associated with later acceptance in the match-run: Public Health Service increased-risk donor status (adjusted odds ratio [aOR] 2.49, 95% confidence interval [CI] 2.29-2.69), holiday or weekend procurement (aOR 1.11, 95% CI 1.07-1.16), shorter donor stature (aOR 1.53 for <150 cm vs reference >180 cm, 95% CI 1.28-1.94), and procurement in an area with higher intensity of market competition (aOR 1.71, 95% CI 1.62-1.78) and with the longest waiting times (aOR 1.41, 95% CI 1.34-1.49). Later acceptance in the match-run was associated with delayed graft function but not all-cause allograft failure (adjusted hazard ratio 1.01, 95% CI 0.96-1.07). Study limitations include a lack of match-run data for discarded organs and the possibility of sequence inaccuracies for some nonlocal matches. Interventions are needed to reduce turndowns of viable organs, especially when decisions are driven by infectious risk, weekend or holiday procurement, geography, or other donor characteristics unrelated to allograft quality.

Indexed as

Donor SelectionGraft SurvivalAdolescentAdultAllograftsFemaleFollow-Up StudiesGlomerular Filtration RateHumansKidney Failure, ChronicKidney Function TestsKidney TransplantationMaleMiddle AgedPrognosisRegistriesclinical research/practicedonors and donation: deceasedethics and public policykidney (allograft) function/dysfunctionkidney transplantation/nephrologyorgan acceptanceorgan allocationorgan procurement and allocationwaitlist management

Identifiers

PMID28758329
PMCPMC5790617
OpenAlexW2740668243

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.