Evidence map›Paper›PMID 28758155›Full record

ArticleKidney international reports2017

Barry I Freedman, Michael V Rocco, Jeffrey T Bates, Michel Chonchol, Amret T Hawfield, James P Lash, Vasilios Papademetriou, John R Sedor, Karen Servilla, Paul L Kimmel and 3 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Journal of the American Society of Nephrology : JASN · 2019
    Pooled it
  2. Trial
  3. Update on APOL1 and chronic kidney diseases in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  4. Kidney international reports · 2025
    Article
  5. Journal of the American Heart Association · 2023
    Article
  6. The metabolic effects of APOL1 in humans.Pflugers Archiv : European journal of physiology · 2023
    Review
  7. Review
  8. Arteriosclerosis, thrombosis, and vascular biology · 2021
    Article
  9. Observational
  10. Article
  11. APOL1 Nephropathy Risk Alleles and Mortality in African American Adults: A Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
  12. Association ofCirculation · 2019
    Article
  13. Review
  14. The Impact of APOL1 on Chronic Kidney Disease and Hypertension.Advances in chronic kidney disease · 2019
    Review
  15. Article
  16. SPRINT and the Kidney: What Have We Learned?Current hypertension reports · 2018
    Review
  17. Observational
  18. Circulation. Genomic and precision medicine · 2018
    Article
  19. HDL in CKD-The Devil Is in the Detail.Journal of the American Society of Nephrology : JASN · 2018
    Review
  20. Apolipoprotein L1 nephropathies: 2017 in review.Current opinion in nephrology and hypertension · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Barry I FreedmanDepartment of Internal Medicine, Section on Nephrology; Wake Forest School of Medicine, Winston-Salem, NC.
Michael V RoccoDepartment of Internal Medicine, Section on Nephrology; Wake Forest School of Medicine, Winston-Salem, NC.
Jeffrey T BatesMichael E. DeBakey Veterans Administration Medical Center and Baylor College of Medicine, Houston, TX.
Michel ChoncholDepartment of Medicine, Division of Renal Diseases and Hypertension; University of Colorado Anschutz Medical Campus, Aurora, CO.
Amret T HawfieldDepartment of Internal Medicine, Section on Nephrology; Wake Forest School of Medicine, Winston-Salem, NC.
James P LashDepartment of Medicine, Division of Nephrology; University of Illinois, Chicago, IL.
Vasilios PapademetriouCenter for Hypertension, Kidney & Vascular Research; Georgetown University Medical Center, Washington, DC.
John R SedorDepartment of Medicine; MetroHealth Medical Center and Department of Physiology and Biophysics; Case Western Reserve University, Cleveland, OH.
Karen ServillaInternal Medicine, Renal Section; New Mexico Veterans Administration Health Care System, Albuquerque, NM.
Paul L KimmelNational Institute of Diabetes and Digestive and Kidney Diseases; Bethesda, MD.
Barry M WallDepartment of Nephrology; University of Tennessee Health Science Center and Veterans Affairs Medical Center, Memphis, TN.
Nicholas M PajewskiDepartment of Biostatistical Sciences, Division of Public Health Sciences; Wake Forest School of Medicine, Winston-Salem, NC.
SPRINT Research Group
Wake Forest University · USGeorgetown University · USMetroHealth Medical Center · USMichael E. DeBakey VA Medical Center · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNew Mexico VA Health Care System · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Illinois Chicago · USUniversity of Tennessee Health Science Center · US

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025771 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2008 to 2011
$17.6M
NCATS NIH HHS UL1 TR000002NCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1 TR000050NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR000073NCATS NIH HHS UL1 TR000075NCATS NIH HHS UL1 TR000093NCATS NIH HHS UL1 TR000105NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR001064NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR001860NCATS NIH HHS UL1 TR002240NCRR NIH HHS UL1 RR024134NCRR NIH HHS UL1 RR025752NCRR NIH HHS UL1 RR025755NCRR NIH HHS UL1 RR025771NHLBI NIH HHS HHSN268200900040CNHLBI NIH HHS HHSN268200900046CNHLBI NIH HHS HHSN268200900047CNHLBI NIH HHS HHSN268200900048CNHLBI NIH HHS HHSN268200900049CNIDDK NIH HHS R01 DK097836NIGMS NIH HHS P30 GM103337
6 · The paper itself

Abstract

introductionRelationships between apolipoprotein L1 gene (

methodsCox proportional hazards regression models were employed adjusting for age, sex, African ancestry proportion, and treatment group (systolic blood pressure target of <120 mm Hg versus <140 mm Hg).

resultsFourteen percent of participants had two

conclusion

Indexed as

African AmericansalbuminuriaAPOL1cardiovascular diseasechronic kidney diseaseSPRINT

Identifiers

PMID28758155
PMCPMC5527675
OpenAlexW2602794452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.