Evidence map›Paper›PMID 28758121›Full record

ReviewBioMed research international2017

Metabolomics and Cardiology: Toward the Path of Perinatal Programming and Personalized Medicine.

Roberta Pintus, Pier Paolo Bassareo, Angelica Dessì, Martino Deidda, Giuseppe Mercuro, Vassilios Fanos

Abstract readReview
In one paragraph

Review in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. How could metabolomics change pediatric health?Italian journal of pediatrics · 2020
    Review
  6. Background, current role, and potential applications of radiogenomics.Journal of magnetic resonance imaging : JMRI · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roberta PintusDepartment of Surgery, Neonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, University of Cagliari, Policlinico Universitario, Strada Statale 554, Km 4.500, Bivio di Sestu, Monserrato, 09042 Cagliari, Italy.
Pier Paolo BassareoDepartment of Medical Sciences "M. Aresu", Unit of Cardiology and Angiology, University of Cagliari, Policlinico Universitario, Strada Statale 554, Km 4.500, Bivio di Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0002-8374-0260
Angelica DessìDepartment of Surgery, Neonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, University of Cagliari, Policlinico Universitario, Strada Statale 554, Km 4.500, Bivio di Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0002-1154-2118
Martino DeiddaDepartment of Medical Sciences "M. Aresu", Unit of Cardiology and Angiology, University of Cagliari, Policlinico Universitario, Strada Statale 554, Km 4.500, Bivio di Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0002-3725-7614
Giuseppe MercuroDepartment of Medical Sciences "M. Aresu", Unit of Cardiology and Angiology, University of Cagliari, Policlinico Universitario, Strada Statale 554, Km 4.500, Bivio di Sestu, Monserrato, 09042 Cagliari, Italy.
Vassilios FanosDepartment of Surgery, Neonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, University of Cagliari, Policlinico Universitario, Strada Statale 554, Km 4.500, Bivio di Sestu, Monserrato, 09042 Cagliari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart diseases are one of the leading causes of death in Western Countries and tend to become chronic, lowering the quality of life of the patients and ending up in a massive cost for the Health Systems and the society. Thus, there is a growing interest in finding new technologies that would allow the physician to effectively treat and prevent cardiac illnesses. Metabolomics is one of the new "omics" sciences enabling creation of a photograph of the metabolic state of an individual exposed to different environmental factors and pathologies. This review analyzed the most recent literature about this technology and its application in cardiology in order to understand the metabolic shifts that occur even before the manifestation of these pathologies to find possible early predictive biomarkers. In this way, it could be possible to find better treatments, ameliorate the patient's quality of life, and lower the death rate. This technology seems to be so promising that several industries are trying to set up kits to immediately assess the metabolites variations in order to provide a faster diagnosis and the best treatment specific for that patient, offering a further step toward the path of the development of a tailored medicine.

Indexed as

AnimalsCardiologyHeart DiseasesHumansMetabolomicsPerinatal CarePrecision Medicine

Identifiers

PMID28758121
PMCPMC5512040

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.