Evidence map›Paper›PMID 28758069›Full record

ArticleToxicology reports2017

Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing.

Anna C Chlebowski, Jane K La Du, Lisa Truong, Staci L Massey Simonich, Robert L Tanguay

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Aryl Hydrocarbon Receptor Mediates Larval Zebrafish Fin Duplication Following Exposure to Benzofluoranthenes.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anna C ChlebowskiDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331.
Jane K La DuDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331.
Lisa TruongDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331.
Staci L Massey SimonichDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331.
Robert L TanguayDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331.
Oregon State University · US

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Robyn L Tanguay · 2009 to 2026
$52.5M
Reducing Susceptibility to Environmental Stress Throughout the Life SpanP30ES000210 · NIEHS · OREGON STATE UNIVERSITY · PI BECKMAN, JOSEPH S · 1985 to 2015
$21.4M
MODE OF ACTION OF ENVIRONMENTAL TOXICANTST32ES007060 · NIEHS · OREGON STATE UNIVERSITY · PI Jamie DeWitt, Siva Kumar Kolluri · 1985 to 2026
$11.6M
Toxicology and Environmental Occurrence of Novel Nitrated PAHsF31ES026037 · NIEHS · OREGON STATE UNIVERSITY · PI CHLEBOWSKI GIULIETTI, ANNA · 2015 to 2017
$62k
NIEHS NIH HHS F31 ES026037NIEHS NIH HHS P30 ES000210NIEHS NIH HHS P42 ES016465NIEHS NIH HHS T32 ES007060
6 · The paper itself

Abstract

Nitroreductase enzymes are responsible for the reduction of nitro functional groups to amino functional groups, and are found in a range of animal models, zebrafish (

Indexed as

nitrated polycyclic aromatic hydrocarbonnitroreductasepharmaceuticalstissue ablationtransgeniczebrafish

Identifiers

PMID28758069
PMCPMC5527975
OpenAlexW2609924903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.