Evidence map›Paper›PMID 28758007›Full record

ArticleJournal of tissue engineering

Re-epithelialization of whole porcine kidneys with renal epithelial cells.

Nafiseh Poornejad, Evan Buckmiller, Lara Schaumann, Haonan Wang, Jonathan Wisco, Beverly Roeder, Paul Reynolds, Alonzo Cook

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Current status and future prospects of decellularized kidney tissue.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2023
    Review
  8. Article
  9. Approaches to kidney replacement therapies-opportunities and challenges.Frontiers in cell and developmental biology · 2022
    Review
  10. Kidney regeneration approaches for translation.World journal of urology · 2020
    Review
  11. In Vivo Performance of Decellularized Vascular Grafts: A Review Article.International journal of molecular sciences · 2018
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nafiseh PoornejadDepartment of Chemical Engineering, Brigham Young University, Provo, UT, USA.
Evan BuckmillerDepartment of Genetics and Biotechnology, Brigham Young University, Provo, UT, USA.
Lara SchaumannDepartment of Chemical Engineering, Brigham Young University, Provo, UT, USA.
Haonan WangDepartment of Electrical Engineering, Brigham Young University, Provo, UT, USA.
Jonathan WiscoDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA.
Beverly RoederDepartment of Biology, Brigham Young University, Provo, UT, USA.
Paul ReynoldsDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA.
Alonzo CookDepartment of Chemical Engineering, Brigham Young University, Provo, UT, USA.
Brigham Young University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decellularized porcine kidneys were recellularized with renal epithelial cells by three methods: perfusion through the vasculature under high pressure, perfusion through the ureter under high pressure, or perfusion through the ureter under moderate vacuum. Histology, scanning electron microscopy, confocal microscopy, and magnetic resonance imaging were used to assess vasculature preservation and the distribution of cells throughout the kidneys. Cells were detected in the magnetic resonance imaging by labeling them with iron oxide. Perfusion of cells through the ureter under moderate vacuum (40 mmHg) produced the most uniform distribution of cells throughout the kidneys.

Indexed as

epithelial cellskidneymagnetic resonance imagingorgan regenerationRecellularization

Identifiers

PMID28758007
PMCPMC5513523
OpenAlexW2736248583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.