Evidence map›Paper›PMID 28757683›Full record

ArticleMediators of inflammation2017

Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1

Anca-Laura Amati, Anna Zakrzewicz, Robin Siebers, Sigrid Wilker, Sarah Heldmann, Dariusz Zakrzewicz, Andreas Hecker, J Michael McIntosh, Winfried Padberg, Veronika Grau

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. ATP-induced cell death: a novel hypothesis for osteoporosis.Frontiers in cell and developmental biology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Anti-inflammatory Activity of the Protein Z-Dependent Protease Inhibitor.TH open : companion journal to thrombosis and haemostasis · 2021
    Article
  12. Review
  13. Macrophage polarization is linked to CaJournal of lipid research · 2020
    Article
  14. Article
  15. Cryptotanshinone Ameliorates Radiation-Induced Lung Injury in Rats.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Anca-Laura AmatiLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
Anna ZakrzewiczLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
Robin SiebersLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
Sigrid WilkerLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
Sarah HeldmannLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
Dariusz ZakrzewiczDepartment of Biochemistry, Faculty of Medicine, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
Andreas HeckerLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
J Michael McIntoshGeorge E. Wahlen Veterans Affairs Medical Center, Salt Lake City, UT, USA.
Winfried PadbergLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.
Veronika GrauLaboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, Giessen, Germany.ORCID 0000-0001-7512-2051
Justus-Liebig-Universität Gießen · DEUniversities of Giessen and Marburg Lung Center · DEUniversity of Utah · US

Funding

Venoms, Biological Resources, Molecular BiologyP01GM048677 · NIGMS · UNIVERSITY OF UTAH · PI BANDYOPADHYAY, PRADIP K · 1993 to 2018
$32.2M
Novel nAChR-Targeted PeptidesR01GM103801 · NIGMS · UNIVERSITY OF UTAH · PI MCINTOSH, J MICHAEL · 2012 to 2019
$2.4M
NIGMS NIH HHS P01 GM048677NIGMS NIH HHS R01 GM103801
6 · The paper itself

Abstract

Chemokines and ATP are among the mediators of inflammatory sites that can enter the circulation via damaged blood vessels. The main function of chemokines is leukocyte mobilization, and ATP typically triggers inflammasome assembly. IL-1

Indexed as

Adenosine TriphosphateBlotting, WesternCell Line, TumorCells, CulturedChemokine CCL3Chemokine CCL4Chemokine CCL5ChemokinesElectrophoresis, Polyacrylamide GelHumansInterleukin-1betaMonocytesU937 CellsAdenosine TriphosphateChemokine CCL3Chemokine CCL4Chemokine CCL5ChemokinesInterleukin-1beta

Identifiers

PMID28757683
PMCPMC5516742
OpenAlexW2733205940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.