ArticleInternational journal of obesity (2005)2018
Birth by cesarean section in relation to adult offspring overweight and biomarkers of cardiometabolic risk.
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Caesarean section and obesity in young adult offspring: Update of a systematic review with meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Sex modulates the long-term effects of delivery mode on microbiota-gut barrier crosstalk and colitis susceptibility in mice.Gut microbes · 2026Article
- Intrapartum caesarean delivery and childhood BMI trajectories in relation to the infant gut microbiome in the VDAART prospective birth cohort.EBioMedicine · 2026Article
- Assessing Transportation Barriers to Maternal Care for Black Women in Los Angeles County.International journal of environmental research and public health · 2025Observational
- Delivery by cesarean section leads to heavier adult bodyweight in prairie voles (Microtus ochrogaster).Hormones and behavior · 2024Article
- Alpha-1 antitrypsin deficiency and pregnancy complications and birth outcomes: A population-based cohort study in Denmark.PloS one · 2024Article
- Evaluation of Birth by Cesarean Delivery and Development of Early-Onset Colorectal Cancer.JAMA network open · 2023Article
- Lasting consequences on physiology and social behavior following cesarean delivery in prairie voles.Hormones and behavior · 2023Article
- Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet.Physiology & behavior · 2023Article
- Article
- Caesarean delivery is associated with increased blood pressure in young adult offspring.Scientific reports · 2021Article
- Association of gestational weight gain with cesarean section: a prospective birth cohort study in Southwest China.BMC pregnancy and childbirth · 2021Article
- Birth signalling hormones and the developmental consequences of caesarean delivery.Journal of neuroendocrinology · 2021Review
- Perinatal environment shapes microbiota colonization and infant growth: impact on host response and intestinal function.Microbiome · 2020Article
- Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study.BMJ open · 2020Article
- Association of Birth by Cesarean Delivery With Obesity and Type 2 Diabetes Among Adult Women.JAMA network open · 2020Article
- The association between caesarean section delivery and later life obesity in 21-24 year olds in an Urban South African birth cohort.PloS one · 2019Article
- Caesarean section delivery and childhood obesity in a British longitudinal cohort study.PloS one · 2019Article
- The Impact of Caesarean Section on the Risk of Childhood Overweight and Obesity: New Evidence from a Contemporary Cohort Study.Scientific reports · 2018Article
- Nutrition in the First 1000 Days: Ten Practices to Minimize Obesity Emerging from Published Science.International journal of environmental research and public health · 2017Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundBirth by Cesarean section (C-section) may increase the risk for non-communicable diseases. We aimed to examine the relation of birth by C-section with offspring overweight and markers of cardiometabolic risk in a prospective observational cohort with 20 years of follow-up.
methodsThe Danish Fetal Origins Cohort enrolled 965 pregnant women in 1988-1989. In 2008, a follow-up study of the offspring was completed. The offspring were invited to participate in a clinical examination with measurements of anthropometry and a fasting blood sample (n=443). In addition, 252 offspring completed a self-administered questionnaire with questions on height and weight, leaving us with a study sample of 695 offspring. Offspring overweight at 20 years was defined as body mass index (BMI)⩾25 kg m
resultsIn the cohort, 7% were born by C-section, and at age 20 years, 18% of the offspring had a BMI ⩾25 kg m
conclusionBirth by C-section was associated with higher frequency of dysmetabolic traits in offspring independently of shared risk factors. Further research aimed at replicating these findings and elucidating the underlying biological mechanisms of this relation is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.