ArticleInternational journal of obesity (2005)2018
Education as a moderator of genetic risk for higher body mass index: prospective cohort study from childhood to adulthood.
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Educational attainment and diabetes risk: triangulation evidence from UK Biobank prospective cohort, NHANES 2011-2018, and cross-trait genomics analyses.Frontiers in endocrinology · 2026Article
- Healthy lifestyle practice correlates with decreased obesity prevalence in individuals with high polygenic risk: TMM CommCohort study.Journal of human genetics · 2025Article
- Association of educational attainment with esophageal cancer, Barrett's esophagus, and gastroesophageal reflux disease, and the mediating role of modifiable risk factors: A Mendelian randomization study.Frontiers in public health · 2023Article
- Modeling Interaction and Dispersion Effects in the Analysis of Gene-by-Environment Interaction.Behavior genetics · 2022Article
- Genetic propensity for obesity, socioeconomic position, and trajectories of body mass index in older adults.Scientific reports · 2021Article
- Neighborhood deprivation index is associated with weight status among long-term survivors of childhood acute lymphoblastic leukemia.Journal of cancer survivorship : research and practice · 2021Article
- Performing different kinds of physical exercise differentially attenuates the genetic effects on obesity measures: Evidence from 18,424 Taiwan Biobank participants.PLoS genetics · 2019Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe life-course development of body mass index (BMI) may be driven by interactions between genes and obesity-inducing social environments. We examined whether lower parental or own education accentuates the genetic risk for higher BMI over the life course, and whether diet and physical activity account for the educational differences in genetic associations with BMI. SUBJECTS/
methodsThe study comprised 2441 participants (1319 women, 3-18 years at baseline) from the prospective, population-based Cardiovascular Risk in Young Finns Study. BMI (kg/m
resultsMean BMI increased from 22.6 to 26.6 kg/m
conclusionsIn this prospective study, the association of a risk score of 97 genetic variants with BMI was stronger among those with low compared with high education. This suggests lower education in adulthood accentuates the risk of higher BMI in people at genetic risk.
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