Evidence map›Paper›PMID 28757590›Full record

ArticleInternational journal of molecular sciences2017

Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Bladder Cancer Cells via Modulation of STAT3-CCL2 Signaling.

Sung-Ying Huang, Shu-Fang Chang, Kuan-Fu Liao, Sheng-Chun Chiu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. The Role of Natural Compounds in Bladder Urothelial Carcinoma Treatment.International journal of molecular sciences · 2026
    Review
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  7. Review
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  11. Article
  12. Review
  13. Article
  14. Frontiers in pharmacology · 2022
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Vimentin as a target for the treatment of COVID-19.BMJ open respiratory research · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Sung-Ying HuangDepartment of Ophthalmology, Hsinchu Mackay Memorial Hospital, No. 690, Sec. 2, Guangfu Rd., East Dist, Hsinchu City 30071, Taiwan. hopes929@gmail.com.
Shu-Fang ChangDepartment of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 88, Section 1, Fengxing Road, Tanzi Dist., Taichung City 427, Taiwan. fantac10@gmail.com.
Kuan-Fu LiaoGraduate Institute of Integrated Medicine, China Medical University, No. 91, Hsueh-Shih Road, Taichung City 427, Taiwan. kuanfuliaog@gmail.com.
Sheng-Chun ChiuDepartment of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 88, Section 1, Fengxing Road, Tanzi Dist., Taichung City 427, Taiwan. tc1271201@tzuchi.com.tw.
China Medical University · TWMackay Memorial Hospital · TWTaipei Tzu Chi Hospital · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tanshinone IIA (Tan-IIA) is an extract from the widely used traditional Chinese medicine (TCM) Danshen (

Indexed as

AbietanesAnimalsAntineoplastic Agents, PhytogenicCell Line, TumorCell MovementChemokine CCL2Epithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansMiceNeoplasm InvasivenessPhosphorylationSignal TransductionSTAT3 Transcription FactorUrinary Bladder NeoplasmsXenograft Model Antitumor AssaysAbietanesAntineoplastic Agents, PhytogenicCCL2 protein, humanChemokine CCL2STAT3 protein, humanSTAT3 Transcription Factortanshinonebladder cancerchemokine (C-C motif) ligand 2epithelial-mesenchymal transitionsignal transducer and activator of transcription 3tanshinone IIA

Identifiers

PMID28757590
PMCPMC5578008
OpenAlexW2738689068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.