Evidence map›Paper›PMID 28757239›Full record

ReviewMolecular genetics and metabolism2017

Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis.

Mark C Wilkes, Claire E Repellin, Kathleen M Sakamoto

Open access · greenAbstract readReview
In one paragraph

Review in Molecular genetics and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Epitranscriptomic alterations induced by environmental toxins: implications for RNA modifications and disease.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Review
  3. Review
  4. LncRNAJournal of thoracic disease · 2023
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Toxicogenomics: A 2020 Vision.Trends in pharmacological sciences · 2019
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Mark C WilkesDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Claire E RepellinSRI International, Biosciences Division, Menlo Park, CA, USA.
Kathleen M SakamotoDivision of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: kmsakamo@stanford.edu.
SRI International · USStanford Medicine · USStanford University · US

Funding

Training in Pediatric Nonmalignant Hematology and Stem Cell BiologyT32DK098132 · NIDDK · STANFORD UNIVERSITY · PI SAKAMOTO, KATHLEEN M · 2014 to 2022
$1.9M
Signaling Pathways in MDSR01DK107286 · NIDDK · STANFORD UNIVERSITY · PI SAKAMOTO, KATHLEEN M · 2016 to 2019
$1.4M
NIDDK NIH HHS R01 DK107286NIDDK NIH HHS T32 DK098132
6 · The paper itself

Abstract

The role of non-coding Ribonucleic Acids (ncRNAs) in biology is currently an area of intense focus. Hematopoiesis requires rapidly changing regulatory molecules to guide appropriate differentiation and ncRNA are well suited for this. It is not surprising that virtually all aspects of hematopoiesis have roles for ncRNAs assigned to them and doubtlessly much more await characterization. Stem cell maintenance, lymphoid, myeloid and erythroid differentiation are all regulated by various ncRNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and various transposable elements within the genome. As our understanding of the many and complex ncRNA roles continues to grow, new discoveries are challenging the existing classification schemes. In this review we briefly overview the broad categories of ncRNAs and discuss a few examples regulating normal and aberrant hematopoiesis.

Indexed as

AnimalsDNA Transposable ElementsErythroid CellsGene Expression RegulationGenome, HumanHematopoiesisHumansMiceMicroRNAsRNA, MessengerRNA, UntranslatedStem CellsDNA Transposable ElementsMicroRNAsRNA, MessengerRNA, Untranslated

Identifiers

PMID28757239
PMCPMC5722683
OpenAlexW2739203481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.