ArticleVeterinary microbiology2017
Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014.
Article in Veterinary microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- A descriptive analysis of Streptococcus suis-associated disease in Irish pigs from 2010 to 2024: serotypes, pathology, and antimicrobial resistance.Irish veterinary journal · 2026Article
- Bayesian network models to assess antimicrobial resistance patterns of Streptococcus suis isolated from swine production systems in the United States between 2014-2021.PLoS computational biology · 2026Article
- Pan-European analysis shows stable, low antimicrobial resistance in most bovine and porcine respiratory tract pathogens.Frontiers in microbiology · 2026Article
- Review
- Genomic characterization and virulence of Streptococcus suis serotype 7 sequence type 373 of clonal complex 94.Veterinary research · 2025Article
- Serotype distribution and antimicrobial susceptibility of Streptococcus suis isolates from porcine diagnostic samples in Hungary, 2020-2023.Porcine health management · 2025Article
- Multiple Drug ResistantAntibiotics (Basel, Switzerland) · 2024Article
- Antimicrobial Resistance ofMicroorganisms · 2023Article
- Antimicrobial resistance profiles ofJournal of clinical microbiology · 2023Article
- Susceptibility ofAntibiotics (Basel, Switzerland) · 2023Article
- Pharmacokinetics and Pharmacodynamics of Florfenicol in Plasma and Synovial Fluid of Pigs at a Dose of 30 mg/kgAntibiotics (Basel, Switzerland) · 2023Article
- Genomic comparison of two Streptococcus suis serotype 1 strains recovered from porcine and human disease cases.Scientific reports · 2023Article
- Relationship between Penicillin-Binding Proteins Alterations and β-Lactams Non-Susceptibility of Diseased Pig-IsolatedAntibiotics (Basel, Switzerland) · 2023Article
- InvasiveFrontiers in cellular and infection microbiology · 2023Article
- Genomic characterization and virulence of Streptococcus suis serotype 4 clonal complex 94 recovered from human and swine samples.PloS one · 2023Article
- Resistance ofAntibiotics (Basel, Switzerland) · 2022Article
- Synthesis of Oligosaccharides Resembling theOrganic letters · 2022Article
- Comparative analysis of Streptococcus suis genomes identifies novel candidate virulence-associated genes in North American isolates.Veterinary research · 2022Article
- d-enantiomers of CATH-2 enhance the response of macrophages againstJournal of advanced research · 2022Article
- Synovial and Systemic Pharmacokinetics of Florfenicol and PK/PD Integration againstPharmaceutics · 2022Article
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14 authors.
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Abstract
Antimicrobial resistance in Streptococcus suis, a global zoonotic pathogen of pigs, has been mostly studied only in diseased animals using surveys that have not evaluated changes over time. We compared patterns of resistance between S. suis isolates from clinical cases of disease (CC) and non-clinical case (NCC) pigs in England, collected over two discrete periods, 2009-2011 and 2013-2014. Minimum inhibitory concentrations (MIC) of 17 antimicrobials (nine classes) were determined on 405 S. suis isolates categorised by sampling period and disease association to assess changes in resistance over time and association with disease. First, isolates were characterized as resistant or susceptible using published clinical breakpoints. Second, epidemiological cut-offs (ECOFF) were derived from MIC values, and isolates classified as wild type (WT) below the ECOFF and non-wild type (NWT) above the ECOFF. Finally, isolate subsets were analysed for shifts in MIC distribution. NCC isolates were more resistant than CC isolates to cephalosporins, penams, pleuromutilins, potentiated sulphonamides and tetracyclines in both study periods. Resistance levels among CC isolates increased in 2013-2014 relative to 2009-2011 for antimicrobials including aminoglycosides, cephalosporins, fluoroquinolones, pleuromutilins, potentiated sulphonamides and tetracyclines. The prevalence of isolates categorised as NWT for five or more classes of antimicrobials was greater among NCC than CC isolates for both time periods, and increased with time. This study used standardised methods to identify significant shifts in antimicrobial resistance phenotypes of S. suis isolated from pigs in England, not only over time but also between isolates from known clinical cases or disease-free pigs.
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