ArticleAddictive behaviors2018
Developing a scale of domains of negative consequences of chronic heroin use.
Article in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- The measurement of harm reduction goals and outcomes for substance use: Current state and future directions.Journal of prevention and health promotion · 2026Article
- Attention-deficit/hyperactivity disorder combined subtype exacerbates opioid use disorder consequences: Mediation by impulsive phenotypes.Drug and alcohol dependence · 2024Article
- Mediational pathways among drug use initiation, use-related consequences, and quit attempts.Drug and alcohol dependence reports · 2024Article
- Experiences of healthcare and substance use treatment provider-based stigma among patients receiving methadone.Drug and alcohol dependence reports · 2023Article
- Anhedonia modulates benzodiazepine and opioid demand among persons in treatment for opioid use disorder.Frontiers in psychiatry · 2023Article
- Long-term effects of opioid overdose prevention and response training on medical student knowledge and attitudes toward opioid overdose: A pilot study.Addictive behaviors · 2022Article
- Comorbid Affective and Substance Use Disorders of Medicaid/Medicare Beneficiaries at an Opioid Treatment Program Serving Small Urban and Rural Communities.Frontiers in psychiatry · 2022Article
- Environmental enrichment reduces heroin seeking following incubation of craving in both male and female rats.Drug and alcohol dependence · 2021Article
- β-Arrestin 2 (ARRB2) Polymorphism is Associated With Adverse Consequences of Chronic Heroin Use.The American journal on addictions · 2021Article
- A Comparison of Substance Use Patterns Among Lifetime Heroin-Injecting Individuals By Racial Groups.Addiction research & theory · 2020Article
- History of regular nonmedical sedative and/or alcohol use differentiates substance-use patterns and consequences among chronic heroin users.Addictive behaviors · 2019Article
- What defines a clinically meaningful outcome in the treatment of substance use disorders: reductions in direct consequences of drug use or improvement in overall functioning?Addiction (Abingdon, England) · 2019Article
- Factors associated with sedative use and misuse among heroin users.Drug and alcohol dependence · 2018Article
- Mediational Pathways Among Trait Impulsivity, Heroin-use Consequences, and Current Mood State.Addiction research & theory · 2018Article
- An examination of correlates of simultaneous opioid and benzodiazepine use among patients in medication treatment for opioid use disorder in a small midwestern community.Journal of addictive diseasesArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundChronic use of heroin typically leads to numerous negative life consequences and serious clinical impairment. Increased negative consequences can result in poor treatment outcomes as well as adverse health effects and impaired social functioning. Certain risk factors, including early substance use initiation, concurrent use of other illicit substances, and injection drug use are associated with an increase in negative consequences. This study examined whether there are unique domains of heroin consequences and, if so, whether these domains are related to specific substance use characteristics.
methodsData regarding substance use characteristics were collected from 370 non-treatment seeking, heroin-using, 18 to 55year-old participants from the Detroit metropolitan area. Principal component analysis (PCA) was used to analyze the factor structure of 21 negative heroin consequence items.
resultsPCA demonstrated that heroin consequences could be divided into 5 unique domains. These unique domains were related to specific substance use characteristics and heroin consequence domains. Injection heroin use was significantly associated with increased Factor 1 consequences (primarily acute medical problems) but not with consequences in other domains. Certain substance use characteristics, such as injection status and earlier onset of marijuana use, were associated with increased consequences in specific domains.
conclusionsThese findings support the existence of unique domains of negative consequences, and indicate that some risk factors (e.g. injection use) may be specific to these domains. Potential tailored-treatment strategies aimed at improving treatment engagement and reducing harm for heroin use based on person-specific risks and negative consequences are discussed.
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