Evidence map›Paper›PMID 28756783›Full record

ArticleEpidemiology and infection2017

Pork products associated with human infection caused by an emerging phylotype of hepatitis E virus in England and Wales.

B Said, M Usdin, F Warburton, S Ijaz, R S Tedder, D Morgan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Hepatitis E virus genotype 3 microbiological surveillance by the Spanish Reference Laboratory: geographic distribution and phylogenetic analysis of subtypes from 2009 to 2019.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  5. Article
  6. Article
  7. Epidemiology of Hepatitis E in 2017 in Bavaria, Germany.Food and environmental virology · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Epidemiology and genotype 3 subtype dynamics of hepatitis E virus in Belgium, 2010 to 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  16. Hepatitis E virus in blood donors in England, 2016 to 2017: from selective to universal screening.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  17. Review
  18. Article
  19. Hepatitis E virus (HEV) in Scotland: evidence of recent increase in viral circulation in humans.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

B SaidNational Infection Service,Public Health England,Colindale,London,UK.
M UsdinNational Infection Service,Public Health England,Colindale,London,UK.
F WarburtonNational Infection Service,Public Health England,Colindale,London,UK.
S IjazNational Infection Service,Public Health England,Colindale,London,UK.
R S TedderNational Infection Service,Public Health England,Colindale,London,UK.
D MorganNational Infection Service,Public Health England,Colindale,London,UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since 2010, human hepatitis E infections have increased in England and Wales. Most cases are locally acquired and caused by hepatitis E virus genotype 3 (HEV G3). HEV G3 is linked to the consumption of pork products. The increase is associated with the emergence of a new phylotype, HEV G3-group 2 (G3-2, also known as G3abcdhij). Sixty individuals with confirmed hepatitis E infection and no history of travel outside the UK were recruited: 19 were infected with HEV G3-group 1 (G3-1 or G3efg) and 41 with G3-2. Epidemiological data relating to usual shopping habits and consumption of ham and sausages were analysed together with typing data to identify any associations with HEV phylotype. Study participants who purchased ham and/or sausage from a major supermarket were more likely to have HEV G3-2 infection (Relative risks 1·85, P = 0·06, CI 0·97-3·53). The HEV G3-2 phylotype has not been detected in indigenous UK pigs and it is suggested that human infections could be the result of consumption of products made from pork originating outside the UK. This does not infer blame on the supermarket but the epidemiology of HEV is dynamic and reflects complex animal husbandry practices which need to be explored further.

Indexed as

AdultAgedAged, 80 and overAnimalsCohort StudiesEnglandFemaleHepatitis EHepatitis E virusHumansMaleMeat ProductsMiddle AgedRed MeatSus scrofaWalesEpidemiologyhepatitis Ezoonoseszoonotic foodborne diseases

Identifiers

PMID28756783
PMCPMC9148778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.