Evidence map›Paper›PMID 28756777›Full record

ArticleBMC biology2017

Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species.

S L Pearce, D F Clarke, P D East, S Elfekih, K H J Gordon, L S Jermiin, A McGaughran, J G Oakeshott, A Papanicolaou, O P Perera and 52 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 127 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 1 pooled it
18.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 1 synthesis or guideline pooled it, 384 citations in OpenAlex.

  1. Genomic investigations of successful invasions: the picture emerging from recent studies.Biological reviews of the Cambridge Philosophical Society · 2025
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67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

62 authors at 18 institutions in 8 countries.

S L PearceCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
D F ClarkeCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
P D EastCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
S ElfekihCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
K H J GordonCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia. karl.gordon@csiro.au.
L S JermiinCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
A McGaughranCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
J G OakeshottCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia. john.oakeshott@csiro.au.
A PapanicolaouCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
O P PereraSouthern Insect Management Research Unit, USDA-ARS, Stoneville, MS, USA.
R V RaneCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
S RichardsHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA. stephenr@bcm.edu.
W T TayCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
T K WalshCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
A AndersonCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
C J AndersonCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
S AsgariSchool of Biological Sciences, University of Queensland, Brisbane St Lucia, QLD, Australia.
P G BoardJohn Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.
A BretschneiderMax Planck Institute of Chemical Ecology, Jena, Germany.
P M CampbellCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
T ChertempsSorbonnes Universités, UPMC Université Paris 06, Institute of Ecology and Environmental Sciences of Paris, Paris, France.
J T ChristellerPlant and Food Research, Mt Albert, Auckland, New Zealand.
C W CoppinCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
S J DownesCSIRO, Narrabri, NSW, Australia.
G DuanResearch School of Biology, Australian National University, Canberra, ACT, Australia.
C A FarnsworthCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
R T GoodSchool of Biological Sciences, University of Melbourne, Parkville, Vic, Australia.
L B HanState Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Y C HanCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
K HatjeMax Planck Institute for Biophysical Chemistry, Gottingen, Germany.
I HorneCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
Y P HuangInstitute of Plant Physiology and Ecology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
D S T HughesHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
E Jacquin-JolyNational Institute for Agricultural Research (INRA), Institute of Ecology and Environmental Sciences of Paris, Versailles, France.
W JamesCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
S JhangianiHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
M KollmarMax Planck Institute for Biophysical Chemistry, Gottingen, Germany.
S S KuwarMax Planck Institute of Chemical Ecology, Jena, Germany.
S LiCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
N-Y LiuCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
M T MaibecheSorbonnes Universités, UPMC Université Paris 06, Institute of Ecology and Environmental Sciences of Paris, Paris, France.
J R MillerJ. Craig Venter Institute, Rockville, MD, USA.
N MontagneSorbonnes Universités, UPMC Université Paris 06, Institute of Ecology and Environmental Sciences of Paris, Paris, France.
T PerrySchool of Biological Sciences, University of Melbourne, Parkville, Vic, Australia.
J QuHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
S V SongSchool of Biological Sciences, University of Melbourne, Parkville, Vic, Australia.
G G SuttonJ. Craig Venter Institute, Rockville, MD, USA.
H VogelMax Planck Institute of Chemical Ecology, Jena, Germany.
B P WalenzJ. Craig Venter Institute, Rockville, MD, USA.
W XuCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
H-J ZhangCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
Z ZouState Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
P BatterhamSchool of Biological Sciences, University of Melbourne, Parkville, Vic, Australia.
O R EdwardsCSIRO, Floreat Park, WA, Australia.
R FeyereisenDepartment of Plant and Environmental Sciences, University of Copenhagen, Thorvaldsensvej, Denmark.
R A GibbsHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
D G HeckelMax Planck Institute of Chemical Ecology, Jena, Germany.
A McGrathCSIRO Black Mountain, GPO Box 1700, Canberra, ACT, 2600, Australia.
C RobinSchool of Biological Sciences, University of Melbourne, Parkville, Vic, Australia.
S E SchererHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
K C WorleyHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Y D WuCollege of Plant Protection, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Commonwealth Scientific and Industrial Research Organisation · AUBaylor College of Medicine · USThe University of Melbourne · AUMax Planck Institute for Chemical Ecology · DEJ. Craig Venter Institute · USAustralian National University · AUInstitut d'écologie et des sciences de l'environnement de Paris · FRInstitute of Zoology · CNMax Planck Institute for Biophysical Chemistry · DENanjing Agricultural University · CNSorbonne Université · FRCenter for Excellence in Molecular Plant Sciences · CNPlant & Food Research · NZSouthern Research Station · USThe University of Queensland · AUUniversity of Copenhagen · DKUniversity of Stirling · GBWestern Sydney University · AU

Funding

Development of Celera Whole Genome Shotgun AssemblerR01GM077117 · NIGMS · J. CRAIG VENTER INSTITUTE, INC. · PI MILLER, JASON RAFE · 2006 to 2011
$2.8M
NIGMS NIH HHS R01 GM077117
6 · The paper itself

Abstract

backgroundHelicoverpa armigera and Helicoverpa zea are major caterpillar pests of Old and New World agriculture, respectively. Both, particularly H. armigera, are extremely polyphagous, and H. armigera has developed resistance to many insecticides. Here we use comparative genomics, transcriptomics and resequencing to elucidate the genetic basis for their properties as pests.

resultsWe find that, prior to their divergence about 1.5 Mya, the H. armigera/H. zea lineage had accumulated up to more than 100 more members of specific detoxification and digestion gene families and more than 100 extra gustatory receptor genes, compared to other lepidopterans with narrower host ranges. The two genomes remain very similar in gene content and order, but H. armigera is more polymorphic overall, and H. zea has lost several detoxification genes, as well as about 50 gustatory receptor genes. It also lacks certain genes and alleles conferring insecticide resistance found in H. armigera. Non-synonymous sites in the expanded gene families above are rapidly diverging, both between paralogues and between orthologues in the two species. Whole genome transcriptomic analyses of H. armigera larvae show widely divergent responses to different host plants, including responses among many of the duplicated detoxification and digestion genes.

conclusionsThe extreme polyphagy of the two heliothines is associated with extensive amplification and neofunctionalisation of genes involved in host finding and use, coupled with versatile transcriptional responses on different hosts. H. armigera's invasion of the Americas in recent years means that hybridisation could generate populations that are both locally adapted and insecticide resistant.

Indexed as

Genome, InsectHerbivoryAnimalsGene Expression ProfilingGenomicsIntroduced SpeciesLarvaMothsSequence Analysis, DNA

Identifiers

PMID28756777
PMCPMC5535293
OpenAlexW2738191634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.