Evidence map›Paper›PMID 28756616›Full record

ArticlePhotochemistry and photobiology2018

PARP-1/PAR Activity in Cultured Human Lens Epithelial Cells Exposed to Two Levels of UVB Light.

Caroline S Cencer, Shravan K Chintala, Tenira J Townsend, Daniel P Feldmann, Mirna A Awrow, Nahrain A Putris, Mason E Geno, Maria G Donovan, Frank J Giblin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Photochemistry and photobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Caroline S CencerEye Research Institute, Oakland University, Rochester, MI.
Shravan K ChintalaEye Research Institute, Oakland University, Rochester, MI.
Tenira J TownsendEye Research Institute, Oakland University, Rochester, MI.
Daniel P FeldmannEye Research Institute, Oakland University, Rochester, MI.
Mirna A AwrowEye Research Institute, Oakland University, Rochester, MI.
Nahrain A PutrisEye Research Institute, Oakland University, Rochester, MI.
Mason E GenoEye Research Institute, Oakland University, Rochester, MI.
Maria G DonovanEye Research Institute, Oakland University, Rochester, MI.
Frank J GiblinEye Research Institute, Oakland University, Rochester, MI.
Oakland University · USSmith-Kettlewell Eye Research Institute · US

Funding

PROTEINS OF NORMAL AND CATARACTOUS LENSESR01EY002027 · NEI · OAKLAND UNIVERSITY · PI GIBLIN, FRANK JOSEPH · 1985 to 2017
$6.1M
Fluorescence Microscope ApplicationS10RR026546 · NCRR · OAKLAND UNIVERSITY · PI GIBLIN, FRANK JOSEPH · 2010 to 2010
$108k
NCRR NIH HHS S10 RR026546NEI NIH HHS R01 EY002027
6 · The paper itself

Abstract

This study investigated poly(ADP-ribose) polymerase-1 (PARP-1) activation in cultured human lens epithelial cells exposed to two levels of UVB light (312 nm peak wavelength), 0.014 and 0.14 J cm

Indexed as

Cell DeathCell LineCell NucleusCell SurvivalDNA DamageEpithelial CellsHumansLens, CrystallineMembrane ProteinsMitochondriaNeoplasm ProteinsPoly (ADP-Ribose) Polymerase-1Reactive Oxygen SpeciesUltraviolet RaysJTB protein, humanMembrane ProteinsNeoplasm ProteinsPARP1 protein, humanPoly (ADP-Ribose) Polymerase-1Reactive Oxygen Species

Identifiers

PMID28756616
PMCPMC5771823
OpenAlexW2740530891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.