ArticleEuropean archives of psychiatry and clinical neuroscience2018
The impact of cognitive insight, self-stigma, and medication compliance on the quality of life in patients with schizophrenia.
Article in European archives of psychiatry and clinical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
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Who cites it
17 citing papers in PubMed.
- The correlation between cumulative burden of mental disorders and self-harm, shame, and insight in young female patients with schizophrenia.European archives of psychiatry and clinical neuroscience · 2025Trial
- Sex-specific predictors of self-stigma reduction in psychosis resulting from metacognitive interventions: Results from a randomized clinical trial.Women's health (London, England)Trial
- The cost of high cognitive insight: chain mediation of stigma and dysfunctional sleep beliefs and attitudes in chronotype among patients with schizophrenia.Frontiers in psychiatry · 2026Article
- Insight Paradox in Patients With Schizophrenia: A Concept Analysis.International journal of mental health nursing · 2025Review
- The Psychosocial Impact of Insight Paradox and Internalized Stigma in Chronic Psychotic Disorders.Behavioral sciences (Basel, Switzerland) · 2025Article
- Validation of the Traditional Chinese Version of the Belief About Medicines Questionnaire-Specific Among Adults with Type 2 Diabetes in Taiwan.Patient preference and adherence · 2025Article
- Internalised Stigma, Self-Esteem and Perceived Social Support as Psychosocial Predictors of Quality of Life in Adult Patients with Schizophrenia.Journal of clinical medicine · 2024Article
- Rates and correlates of medication non-adherence behaviors and attitudes in adult patients with early psychosis.Social psychiatry and psychiatric epidemiology · 2024Article
- Subjective cognitive complaints in first episode psychosis: A focused follow-up on sex effect and alcohol usage.Schizophrenia research. Cognition · 2022Article
- A Cross-Sectional, Questionnaire-Based Study on Drug Treatment Awareness in Schizophrenia Patients and Caregivers: An Unexplored Avenue.Indian journal of psychological medicine · 2022Article
- Characteristics associated with self-reported medication adherence in persons with psychosis referred to psychosocial rehabilitation centers.European archives of psychiatry and clinical neuroscience · 2021Article
- Co-occurring Deficits in Clinical and Cognitive Insight in Prolonged Schizophrenia-Spectrum Disorders: Relationship to Metacognitive Deficits.Schizophrenia bulletin open · 2021Article
- Effects of Mindfulness-Based Cognitive Therapy on Stigma in Female Patients With Schizophrenia.Frontiers in psychiatry · 2021Article
- Relationships between social stigma, stigma experience and self-stigma and impaired quality of life in schizophrenia across three Latin-American countries.European archives of psychiatry and clinical neuroscience · 2020Article
- Adherence to Antihypertensive Medication: An Interview Analysis of Southwest Ugandan Patients' Perspectives.Annals of global health · 2020Article
- Correlation Analysis of the Quality of Family Functioning and Subjective Quality of Life in Rehabilitation Patients Living with Schizophrenia in the Community.International journal of environmental research and public health · 2020Article
- Cognitive insight and quality of life among psychiatric outpatients.BMC psychiatry · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Impaired quality of life (QoL) is a common and clinically relevant feature of schizophrenia. In the present study, we attempted to formulate a model of QoL in the chronic stage of schizophrenia by including key variables-namely cognitive insight, self-stigma, insight into treatment, and medication compliance-that were proposed as its significant predictors in previous studies. We employed structural equation modeling (SEM) to simultaneously test the associations between these variables. A total of 170 community-dwelling patients with schizophrenia participated in this study. Cognitive insight, self-stigma, insight into treatment, medication compliance, and QoL were assessed through self-reporting. Symptoms were rated by interviewers. The influences of cognitive insight, stigma, insight into treatment, and medication compliance on QoL were supported using SEM. Our findings indicated that cognitive insight had a significant, positive, and direct effect on both self-stigma and insight into treatment; in contrast, it had a negative and direct effect on medication compliance. Notably, no evidence indicated a direct effect of cognitive insight on QoL. Thus, individuals with high cognitive insight reported low QoL because of stigma, low medication compliance, and their increased insight into treatment. In contrast, cognitive insight might indirectly ameliorate QoL mediated by the effect of insight into treatment on medication compliance. The findings provide additional support of the links between cognitive and clinical insight, self-stigma, medication compliance, and QoL in those with schizophrenia and suggest the need for screening and intervention services appropriate for this high-risk population.
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Registered trials
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