ArticleThorax2018
Perspectives of survivors, families and researchers on key outcomes for research in acute respiratory failure.
Article in Thorax, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2024Guideline
- Pooled it
- Long-term outcomes after treatment of delirium during critical illness with antipsychotics (MIND-USA): a randomised, placebo-controlled, phase 3 trial.The Lancet. Respiratory medicine · 2024Trial
- Identifying distinct clusters of ICU survivors by integrating demographic, pre-admission quality of life, and clinical data: a large prospective cohort study.Intensive care medicine · 2025Article
- Post-Intensive Care Syndrome: Physical Impairments and Function.Critical care clinics · 2025Review
- [Post-Intensive Care Syndrome: functional impairments of critical illness survivors].Die Anaesthesiologie · 2025Review
- Long-term outcomes in nutrition trials: after all, this is what our patients are looking for!!Intensive care medicine · 2024Article
- Outcome Measures to Evaluate Functional Recovery in Survivors of Respiratory Failure: A Scoping Review.CHEST critical care · 2024Article
- Article
- Calculating Route: Functional Trajectories and Long-Term Outcomes in Survivors of Severe COVID-19.The journal of nutrition, health & aging · 2023Article
- Post-Intensive Care Syndrome after Critical Illness: An Imperative for Effective Prevention.Journal of clinical medicine · 2022Article
- Putting measurement on a diet: development of a core set of indicators for quality improvement in the ICU using a Delphi method.BMC health services research · 2022Article
- Survivorship of Patients After Long Intensive Care Stay With Exploration and Experience in a New Zealand Cohort (SPLIT ENZ): Protocol for a Mixed Methods Study.JMIR research protocols · 2022Article
- Article
- Feasibility of Extracting Meaningful Patient Centered Outcomes From the Electronic Health Record Following Critical Illness in the Elderly.Frontiers in medicine · 2022Article
- Long-Term Outcomes after Delirium in the ICU: Addressing Gaps in Our Knowledge.American journal of respiratory and critical care medicine · 2021Article
- Cardiopulmonary Exercise Testing in Critically Ill Coronavirus Disease 2019 Survivors: Evidence of a Sustained Exercise Intolerance and Hypermetabolism.Critical care explorations · 2021Article
- Beyond survival: identifying what matters to survivors of critical illness.Critical care (London, England) · 2021Article
- Ten reasons for focusing on the care we provide for family members of critically ill patients with COVID-19.Intensive care medicine · 2021Article
- Muscular weakness and muscle wasting in the critically ill.Journal of cachexia, sarcopenia and muscle · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThere is heterogeneity among the outcomes evaluated in studies of survivors of acute respiratory failure (ARF).
aimTo evaluate the importance of specific outcome domains to acute respiratory distress syndrome (ARDS) survivors, their family members and clinical researchers.
methodsNineteen outcome domains were identified from the National Institutes of Health's Patient Reported Outcomes Measurement Information System; WHO's International Classification of Functioning, Disability, and Health; Society of Critical Care Medicine's Post-Intensive Care Syndrome (PICS); as well as patient, clinician and researcher input. We surveyed ARDS survivors, family members and critical care researchers, 279 respondents in total, using a 5-point scale (strongly disagree, disagree, neutral, agree and strongly agree) to rate the importance of measuring each domain in studies of ARF survivors' postdischarge outcomes. MEASUREMENTS AND MAIN
resultsAt least 80% of patients and family members supported (ie, rated 'agree' or 'strongly agree') that 15 of the 19 domains should be measured in all future studies. Among researchers, 6 of 19 domains were supported, with researchers less supportive for all domains, except survival (95% vs 72% support). Overall, four domains were supported by all groups: physical function, cognitive function, return to work or prior activities and mental health.
conclusionPatient, family and researcher groups supported inclusion of outcome domains that fit within the PICS framework. Patients and family members also supported many additional domains, emphasising the importance of including patients/family, along with researchers, in consensus processes to select core outcome domains for future research studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.