Evidence map›Paper›PMID 28756396›Full record

ArticleJournal of epidemiology and community health2017

Reducing chemical exposures at home: opportunities for action.

Ami R Zota, Veena Singla, Gary Adamkiewicz, Susanna D Mitro, Robin E Dodson

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of epidemiology and community health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04242758 (Exploring the Association Between Phthalates Exposure, Measured Through Their Urinary Metabolites, and Renal Function Impairment in Individuals With TYpe 2 Diabetes - SGLT2 Subprotocol), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04242758 phase4unknown statusnot on this mapstarted 2019, after this paper: background citation

Exploring the Association Between Phthalates Exposure, Measured Through Their Urinary Metabolites, and Renal Function Impairment in Individuals With TYpe 2 Diabetes - SGLT2 Subprotocol

TypeinterventionalSponsorUniversity of PisaRan2019 to 2020Enrolled30ConditionsRenal Function Disorder, Glucose Metabolism DisordersArmsDapagliflozin 10 MG, Hydrochlorothiazide 12.5mg
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  15. Application of anEnvironmental health perspectives · 2021
    Article
  16. Spectroscopic Investigation of Increased Fluorescent Intensity of Fluorescent Dyes When Adsorbed onto Polystyrene Microparticles.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ami R ZotaDepartment of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington DC, USA.
Veena SinglaHealth and Environment Program, Natural Resources Defense Council, San Francisco, California, USA.
Gary AdamkiewiczDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Susanna D MitroPopulation Health Sciences Program, Harvard University, Boston, Massachusetts, USA.
Robin E DodsonSilent Spring Institute, Newton, Massachusetts, USA.
Harvard University · USMilken Institute · USNatural Resources Defense Council · USSilent Spring Institute · US

Funding

Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Role of endocrine-disrupting chemicals and social stress on perinatal outcomesR00ES019881 · NIEHS · GEORGE WASHINGTON UNIVERSITY · PI ZOTA, AMI R · 2013 to 2015
$747k
NIEHS NIH HHS R00 ES019881NIEHS NIH HHS T32 ES007069
6 · The paper itself

Abstract

Indoor environments can influence human environmental chemical exposures and, ultimately, public health. Furniture, electronics, personal care and cleaning products, floor coverings and other consumer products contain chemicals that can end up in the indoor air and settled dust. Consumer product chemicals such as phthalates, phenols, flame retardants and per- and polyfluorinated alkyl substances are widely detected in the US general population, including vulnerable populations, and are associated with adverse health effects such as reproductive and endocrine toxicity. We discuss the implications of our recent meta-analysis describing the patterns of chemical exposures and the ubiquity of multiple chemicals in indoor environments. To reduce the likelihood of exposures to these toxic chemicals, we then discuss approaches for exposure mitigation: targeting individual behaviour change, household maintenance and purchasing decisions, consumer advocacy and corporate responsibility in consumer markets, and regulatory action via state/federal policies. There is a need to further develop evidence-based strategies for chemical exposure reduction in each of these areas, given the multi-factorial nature of the problem. Further identifying those at greatest risk; understanding the individual, household and community factors that influence indoor chemical exposures; and developing options for mitigation may substantially improve individuals' exposures and health.

Indexed as

consumer product chemicalsenvironmental policyflame retardantsindoor dustphthalates

Identifiers

PMID28756396
PMCPMC5561392
OpenAlexW2739566238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.