ArticleJournal of vascular surgery2017
Association between arterial stiffness and peripheral artery disease as measured by radial artery tonometry.
Article in Journal of vascular surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Body mass-normalized moderate dose of dietary nitrate intake improves endothelial function and walking capacity in patients with peripheral artery disease.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Trial
- Insulin increases central aortic stiffness in response to hyperglycemia in healthy humans: A randomized four-arm study.Diabetes & vascular disease researchTrial
- First-harmonic attenuation of radial pulse waves as a sensitive marker for vascular aging.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Blood pressure parameters and the risk of chronic limb-threatening ischemia: The Singapore Chinese Health Study.Journal of vascular surgery · 2026Article
- DDR1 Regulates Femoral Arterial Calcification in Lower-Extremity Artery Disease Through NF-Kappa B Activation.Acta physiologica (Oxford, England) · 2026Article
- Arterial stiffness and vascular aging: mechanisms, prevention, and therapy.Signal transduction and targeted therapy · 2025Review
- Association between calf circumference and cardiovascular health indicators in patients with peripheral artery disease.Einstein (Sao Paulo, Brazil) · 2025Article
- Comparison of Parameters for Assessment of Carotid Stiffness and Their Association with Carotid Atherosclerosis in Rural Australian Adults: A Pilot Study.Journal of clinical medicine · 2023Article
- Oscillometric measurement of the ankle-brachial index and the estimated carotid-femoral pulse wave velocity improves the sensitivity of an automated device in screening peripheral artery disease.Frontiers in cardiovascular medicine · 2023Article
- Cardiac Rehabilitation in Peripheral Artery Disease in a Tertiary Center-Impact on Arterial Stiffness and Functional Status after 6 Months.Life (Basel, Switzerland) · 2022Article
- Predictors of arterial stiffness in adolescents and adults with type 1 diabetes: a cross-sectional study.BMJ open diabetes research & care · 2022Article
- Article
- Impact of in-hospital blood pressure variability on clinical outcomes in patients with symptomatic peripheral arterial disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Traditional and non-traditional risk factors for peripheral artery disease development/progression in patients with type 2 diabetes: the Rio de Janeiro type 2 diabetes cohort study.Cardiovascular diabetology · 2021Observational
- Sex modification of the association of the radial augmentation index and incident hypertension in a Chinese community-based population.Journal of geriatric cardiology : JGC · 2021Article
- The association between pulse wave analysis, carotid-femoral pulse wave velocity and peripheral arterial disease in patients with ischemic heart disease.BMC cardiovascular disorders · 2021Article
- Use of the ankle-brachial index combined with the percentage of mean arterial pressure at the ankle to improve prediction of all-cause mortality in type 2 diabetes mellitus: an observational study.Cardiovascular diabetology · 2020Observational
- Radial Artery Tonometry is Associated With Major Adverse Cardiac Events in Patients With Peripheral Artery Disease.The Journal of surgical research · 2019Article
- Serum resistin is associated with impaired endothelial function and a higher rate of adverse cardiac events in patients with peripheral artery disease.Journal of vascular surgery · 2019Article
- Association between critical limb ischemia and arterial stiffness measured by brachial artery oscillometry.Jornal vascular brasileiro · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveArterial stiffness and peripheral artery disease (PAD) are both associated with an elevated risk of major adverse cardiac events; however, the association between arterial stiffness and PAD is less well characterized. The goal of this study was to examine the association between parameters of radial artery tonometry, a noninvasive measure of arterial stiffness, and PAD.
methodsWe conducted a cross-sectional study of 134 vascular surgery outpatients (controls, 33; PAD, 101) using arterial applanation tonometry. Central augmentation index (AIX) normalized to 75 beats/min and peripheral AIX were measured using radial artery pulse wave analysis. Pulse wave velocity was recorded at the carotid and femoral arteries. PAD was defined as symptomatic claudication with an ankle-brachial index of <0.9 or a history of peripheral revascularization. Controls had no history of atherosclerotic vascular disease and an ankle-brachial index ≥0.9.
resultsAmong the 126 participants with high-quality tonometry data, compared with controls (n = 33), patients with PAD (n = 93) were older, with higher rates of hypertension, hyperlipidemia, diabetes, and smoking (P < .05). Patients with PAD also had greater arterial stiffness as measured by central AIX, peripheral AIX, and pulse wave velocity (P < .05). In a multivariable model, a significantly increased odds of PAD was associated with each 10-unit increase in central AIX (odds ratio, 2.1; 95% confidence interval, 1.1-3.9; P = .03) and peripheral AIX (odds ratio, 1.9; 95% confidence interval, 1.2-3.2; P = .01). In addition, central and peripheral AIX were highly correlated (r
conclusionsIn a cross-sectional analysis, arterial stiffness as measured by the AIX is independently associated with PAD, even when adjusting for several atherosclerotic risk factors. Further prospective data are needed to establish whether radial artery tonometry could be a tool for risk stratification in the PAD population.
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