Evidence map›Paper›PMID 28755316›Full record

ArticleHistochemistry and cell biology2017

Deficiency of a membrane skeletal protein, 4.1G, results in myelin abnormalities in the peripheral nervous system.

Yurika Saitoh, Nobuhiko Ohno, Junji Yamauchi, Takeharu Sakamoto, Nobuo Terada

Abstract read
PubMed Publisher
In one paragraph

Article in Histochemistry and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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  13. In focus in HCB.Histochemistry and cell biology · 2019
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  15. In focus in HCB.Histochemistry and cell biology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Yurika SaitohDivision of Health Sciences, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.
Nobuhiko OhnoCenter for Multidisciplinary Brain Research, National Institute for Physiological Science, Okazaki, Aichi, Japan.
Junji YamauchiLaboratory of Molecular Neuroscience and Neurology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Takeharu SakamotoDivision of Molecular Pathology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.
Nobuo TeradaDivision of Health Sciences, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan. nobuot@shinshu-u.ac.jp.
National Institute for Physiological Sciences · JPShinshu University · JPTeikyo University · JPThe University of Tokyo · JPTokyo University of Pharmacy and Life Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously demonstrated that a membrane skeletal molecular complex, 4.1G-membrane palmitoylated protein 6 (MPP6)-cell adhesion molecule 4, is incorporated in Schwann cells in the peripheral nervous system (PNS). In this study, we evaluated motor activity and myelin ultrastructures in 4.1G-deficient (-/-) mice. When suspended by the tail, aged 4.1G

Indexed as

AnimalsImmunohistochemistryMiceMice, KnockoutMicrofilament ProteinsMicroscopy, ElectronMyelin SheathPeripheral Nervous SystemEpb4.1l2 protein, mouseMicrofilament ProteinsInternodesMembrane skeletonMyelinParanodesScaffold protein

Identifiers

PMID28755316
OpenAlexW2741813201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.